癌症手术前预防研究的优先领域:一项国际德尔菲研究。
Research Priorities in Prehabilitation for Patients Undergoing Cancer Surgery: An International Delphi Study.
发表日期:2023 Aug 24
作者:
Pratik Raichurkar, Linda Denehy, Michael Solomon, Cherry Koh, Neil Pillinger, Sophie Hogan, Kate McBride, Sharon Carey, Jenna Bartyn, Nicholas Hirst, Daniel Steffens,
来源:
ANNALS OF SURGICAL ONCOLOGY
摘要:
最近,预防康复试验的数量显著增加。确定关键研究优先事项对指导未来研究方向至关重要。因此,本合作研究的目的是定义在癌症手术患者中的预防康复的关键研究优先事项。我们采用Delphi方法,通过安全的在线平台向来自多个专业、肿瘤流与国家地区的预防康复专家分发了三轮调查问卷。第一轮中,参与者被要求提供基础人口统计学信息,并确定五个最重要的预防康复研究优先事项。在后续的几轮中,参与者被要求在5点列克特量表上对研究优先事项进行排序。如果> 70%的参与者对每个研究优先事项表示一致意见,则视为达成共识。
共有165名预防康复专家参与了研究,包括医生、物理治疗师、营养师、护士和学者,分布在四个大洲。第一轮确定了446个研究优先事项,总结了75个独特的研究问题。经过两轮的调查,确定了前十名国际共识的研究优先事项。包括预防康复对术后多种结果的功效、对特定患者群体的益处、理想的计划构成、成本效益、增强依从性、在新辅助治疗期间的作用以及传递方式。
这项全球合作研究确定了癌症手术患者预防康复的前十个研究优先事项。这些确定的优先事项将指导研究战略、提供未来的预防康复研究方向、支持资源配置,并增强正在进行手术的癌症患者的预防康复证据基础。© 2023. 作者们。
Recently, the number of prehabilitation trials has increased significantly. The identification of key research priorities is vital in guiding future research directions. Thus, the aim of this collaborative study was to define key research priorities in prehabilitation for patients undergoing cancer surgery.The Delphi methodology was implemented over three rounds of surveys distributed to prehabilitation experts from across multiple specialties, tumour streams and countries via a secure online platform. In the first round, participants were asked to provide baseline demographics and to identify five top prehabilitation research priorities. In successive rounds, participants were asked to rank research priorities on a 5-point Likert scale. Consensus was considered if > 70% of participants indicated agreement on each research priority.A total of 165 prehabilitation experts participated, including medical doctors, physiotherapists, dieticians, nurses, and academics across four continents. The first round identified 446 research priorities, collated within 75 unique research questions. Over two successive rounds, a list of 10 research priorities reached international consensus of importance. These included the efficacy of prehabilitation on varied postoperative outcomes, benefit to specific patient groups, ideal programme composition, cost efficacy, enhancing compliance and adherence, effect during neoadjuvant therapies, and modes of delivery.This collaborative international study identified the top 10 research priorities in prehabilitation for patients undergoing cancer surgery. The identified priorities inform research strategies, provide future directions for prehabilitation research, support resource allocation and enhance the prehabilitation evidence base in cancer patients undergoing surgery.© 2023. The Author(s).