量子点（QDs）的已知特性是它们具有特征性的发光性，这使得它们在与某种生物分子功能化后能够可能检测不同类型的癌症。因此，在本研究中，对CdTe/ZnS核壳结构的量子点的物化特性进行了方法论分析，采用了光吸收光谱（UV-Vis）、分子荧光、傅里叶变换红外光谱（FT-IR）、动态光散射（DLS）、X射线衍射（XRD）、透射电子显微镜（TEM）和静电势等技术，这些技术可以验证这些半导体纳米晶体作为目前用于检测小于1厘米特定癌症的常规技术的替代品的光致发光效果。研究包括理论确定带隙能量、纳米晶体的尺寸和摩尔吸光度，从最大激子峰强度对应的波长值进行。还能够验证每个样品的最大强度，从而评估其光致发光响应，并能够确定每个量子点的电荷分布、流体动力学尺寸和表面组成。所得结果与文献报道相符，使其成为预癌症阶段癌症检测的良好候选者。© 2023。作者授予施普林格科学+商业媒体有限责任公司独家许可，施普林格自然出版集团的一部分。

A known property of quantum dots (QDs) is their characteristic luminescence, which would make it possible to detect different types of cancers after being functionalized with some type of biological molecule. For this reason, in the present investigation a methodological analysis of the physicochemical characteristics of the CdTe/ZnS core/shell QDs was carried out, using techniques such as Optical Absorbance Spectroscopy (UV-Vis), Molecular Fluorescence, Fourier Transform Infrared Spectroscopy (FT-IR), Dynamic Light Scattering (DLS), X-Ray Diffraction (XRD), Transmission Electron Microscopy (TEM) and Zeta Potential that allowed to verify the photoluminescent effectiveness of these semiconductor nanocrystals as an alternative to conventional techniques currently used for the detection of specific cancers smaller than 1 cm. The study consisted of theoretically determining the bandgap energy, the size of the nanocrystals and the molar absorptivity from the wavelength value for the maximum intensity of the excitonic peak. It was also possible to verify the maximum intensity for each sample and thus evaluate its photoluminescent response, as well as it was possible to determine the charge distribution, the hydrodynamic size and the surface composition of each quantum dot. The results obtained correspond to what has been reported in the literature, which makes them good candidates for the detection of cancer in precancerous stages.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.