研究动态
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探索比利时的失去年寿命,2004-2019年:一项综合使用概率重新分配方法的分析。

Investigating years of life lost in Belgium, 2004-2019: A comprehensive analysis using a probabilistic redistribution approach.

发表日期:2023 Aug 25
作者: Brecht Devleesschauwer, Aline Scohy, Robby De Pauw, Vanessa Gorasso, Anne Kongs, Elias Neirynck, Peter Verduyckt, Grant M A Wyper, Laura Van den Borre
来源: Alzheimers & Dementia

摘要:

有关由于过早死亡而导致的失去生命年(YLL)的信息对于评估疾病的致命影响以及计算比利时失能调整生活年(DALY)是必不可少的。本研究提出了一种重新分配死因数据的新方法。死因数据由比利时统计局(Statbel)提供。首先,将定义死因的具体ICD-10代码映射到GBD死因清单。其次,将不明确的死因(IDD)重新分配到具体的ICD-10代码。为适应比利时的情况,开发了一个四步骤的概率重分配方法:使用预定义的ICD代码进行重分配、使用多原因死亡数据进行重分配、内部重分配和对所有原因的重分配。最后,我们使用GBD 2019参考寿命表来计算标准预期失去寿命(SEYLL)。在比利时,2004年至2019年间,IDD的比例从31%增加到34%。其中大多数使用预定义的ICD代码进行了重分配(14-15%),其次是使用多原因死亡数据进行重分配(10-12%)。SEYLL的总数从每年的183万减少到173万。在2019年,SEYLL的主要原因是肺癌,占比8.5%,其次是缺血性心脏病(8.1%)和阿尔茨海默病和其他痴呆症(5.7%)。所有结果都可以在在线工具https://burden.sciensano.be/shiny/mortality2019/ 中进行查看。由于重新分配过程为比利时的所有死亡分配了具体死因,这使得首次有可能调查完整的死亡负担。为了估计2004年至2019年间按年龄、性别和地区分别因大量死因而失去的预期寿命,产生了大量估计值。这些估计值对于未来有关比利时失能调整生活年(DALYs)的研究是重要的里程碑。©2023年。BioMed Central Ltd.,Springer Nature的一部分。
Information on years of life lost (YLL) due to premature mortality is instrumental to assess the fatal impact of disease and necessary for the calculation of Belgian disability-adjusted life years (DALYs). This study presents a novel method to reallocate causes of death data.Causes of death data are provided by Statistics Belgium (Statbel). First, the specific ICD-10 codes that define the underlying cause of death are mapped to the GBD cause list. Second, ill-defined deaths (IDDs) are redistributed to specific ICD-10 codes. A four-step probabilistic redistribution was developed to fit the Belgian context: redistribution using predefined ICD codes, redistribution using multiple causes of death data, internal redistribution, and redistribution to all causes. Finally, we used the GBD 2019 reference life table to calculate Standard Expected Years of Life Lost (SEYLL).In Belgium, between 2004 and 2019, IDDs increased from 31 to 34% of all deaths. The majority was redistributed using predefined ICD codes (14-15%), followed by the redistribution using multiple causes of death data (10-12%). The total number of SEYLL decreased from 1.83 to 1.73 million per year. In 2019, the top cause of SEYLL was lung cancer with a share of 8.5%, followed by ischemic heart disease (8.1%) and Alzheimer's disease and other dementias (5.7%). All results are available in an online tool https://burden.sciensano.be/shiny/mortality2019/ .The redistribution process assigned a specific cause of death to all deaths in Belgium, making it possible to investigate the full mortality burden for the first time. A large number of estimates were produced to estimate SEYLL by age, sex, and region for a large number of causes of death and every year between 2004 and 2019. These estimates are important stepping stones for future investigations on Disability-Adjusted Life Years (DALYs) in Belgium.© 2023. BioMed Central Ltd., part of Springer Nature.