口腔黏膜炎是由于干细胞移植引起的常见且具有毁灭性副作用，这种副作用经历于接受化疗或放疗的癌症患者。该病况涉及口腔黏膜的炎症和溃疡，导致疼痛、饮食和言语困难以及感染风险增加。黏膜炎不仅影响癌症患者的生活质量，还影响治疗结果，可能需要减量或延迟治疗。本科学文章提供了黏膜炎的全面综述。本文通过一项荟萃分析的文献回顾，旨在评估激光疗法治疗移植后黏膜炎的疗效。材料和方法：我们于2023年5月3日在三个在线数据库PubMed、Scopus和Web of Science上进行了文献检索。只考虑使用激光疗法治疗患者的研究，只考虑有安慰剂对照组的研究。我们使用Review Manager 5.2.8（Cochrane Collaboration）进行了汇总分析。我们测量了两组（激光和安慰剂）之间的标准均差。结果：本次回顾纳入了230篇论文，其中有227篇被排除。此外，还进行了手工搜索。在检索阶段之后，将三篇文章纳入研究中。整体效果显示激光治疗组的黏膜炎程度与安慰剂组有所不同。荟萃分析显示，在接受激光疗法治疗的患者中，黏膜炎程度有所降低（标准均差-1.34[-1.98；-0.98]，95%可信区间）。结论：激光疗法的应用能够减轻由放疗和化疗引起的口腔黏膜炎的严重程度。我们的研究表明，低能激光疗法在移植黏膜炎的治疗中具有出色的疗效，能够缓解黏膜炎的症状和严重程度。

Oral mucositis is a common and debilitating side effect induced by stem cell transplantation that is experienced by cancer patients undergoing chemotherapy or radiation therapy. This condition involves inflammation and ulceration of the oral mucosa, leading to pain, difficulty with eating and speaking, and an increased risk of infections. Mucositis not only compromises the quality of life for cancer patients, but also affects treatment outcomes and may necessitate dose reductions or treatment delays. This scientific article provides a comprehensive overview of mucositis. The purpose of this literature review with a meta-analysis is to evaluate the efficacy of laser therapy in treating post-transplant mucositis. Materials and methods: A search of the literature from 3 May 2023 was carried out on three online databases, PubMed, Scopus, and Web of Science. Only studies that treated patients with laser therapy were considered; only studies with the placebo-treated control group were considered. Review Manager version 5.2.8 (Cochrane Collaboration) was used for the pooled analysis. We measured the std. mean difference between the two groups (laser and placebo). Results: There were 230 papers included in this review. Two hundred twenty-seven were excluded. Furthermore, a manual search was performed. After the search phase, three articles were considered in the study. The overall effect showed differences in the degree of mucositis in the laser-treated patients compared with the placebo group. The meta-analysis shows a reduction in the degree of mucositis in the patients treated with laser therapy (std. mean difference -1.34 [-1.98; -0.98]; C.I. 95%). Conclusions: The application of laser therapy results in decreased severity of oral mucositis from radiation and chemotherapy. Our study shows that the application of low-level laser therapy in the treatment of transplant mucositis has excellent efficacy in relieving the symptoms and severity of mucositis.