氧化石墨烯（GO）是通过对石墨进行强氧化而得到的多功能材料。在其独特的性质中，最显著的是它可以显著改变许多常见荧光染料和荧光素的荧光性质。这个性质已经被应用于设计新型开关型荧光生物传感平台，用于检测大量生物分子，特别是病理标志物和环境污染物。目前，正在开发新的先进策略，以对抗由病毒或细菌感染以及癌症引起的广泛疾病。本文概述了基于GO的荧光猝灭效应的传感系统的最新应用。

Graphene oxide (GO) is a versatile material obtained by the strong oxidation of graphite. Among its peculiar properties, there is the outstanding ability to significantly alter the fluorescence of many common fluorophores and dyes. This property has been exploited in the design of novel switch-ON and switch-OFF fluorescence biosensing platforms for the detection of a plethora of biomolecules, especially pathological biomarkers and environmental contaminants. Currently, novel advanced strategies are being developed for therapeutic, diagnostic and theranostic approaches to widespread pathologies caused by viral or bacterial agents, as well as to cancer. This work illustrates an overview of the most recent applications of GO-based sensing systems relying on its fluorescence quenching effect.