土壤、空气和水中重金属离子的存在构成了一个重要的全球环境威胁，因为这些离子在食物链中积累，导致慢性疾病（包括但不限于癌症和肾功能衰竭）的增加。迄今为止，已经进行了许多检测的努力，但仍然需要开发出能够进行现场检测重金属离子的敏感、低成本和便携设备。在本研究中，我们将微流控技术和电化学传感相结合，在塑料芯片上利用DNA酶嵌入铂纳米颗粒之间，实现了对重金属离子的选择性检测，从而展示了一种可靠的水污染监测便携解决方案。为了实现基于微流体的重金属离子检测设备，我们提出了一种基于干燥感光层的光刻技术的快速、易于实施的制备方法。作为概念验证，我们利用原型微流控设备实现了对Pb2+离子的检测。

The presence of heavy metal ions in soil, air and water constitutes an important global environmental threat, as these ions accumulate throughout the food chain, contributing to the rise of chronic diseases, including, amongst others, cancer and kidney failure. To date, many efforts have been made for their detection, but there is still a need for the development of sensitive, low-cost, and portable devices able to conduct on-site detection of heavy metal ions. In this work, we combine microfluidic technology and electrochemical sensing in a plastic chip for the selective detection of heavy metal ions utilizing DNAzymes immobilized in between platinum nanoparticles (PtNPs), demonstrating a reliable portable solution for water pollution monitoring. For the realization of the microfluidic-based heavy metal ion detection device, a fast and easy-to-implement fabrication method based on the photolithography of dry photosensitive layers is proposed. As a proof of concept, we demonstrate the detection of Pb2+ ions using the prototype microfluidic device.