金属和非金属掺杂的碳量子点的最新进展:合成和新兴潜在应用
Recent Advancements in Metal and Non-Metal Mixed-Doped Carbon Quantum Dots: Synthesis and Emerging Potential Applications.
发表日期:2023 Aug 14
作者:
Zubair Akram, Ali Raza, Muhammad Mehdi, Anam Arshad, Xiling Deng, Shiguo Sun
来源:
BIOSENSORS & BIOELECTRONICS
摘要:
在纳米技术领域,通过金属和非金属的混合掺杂合成碳量子点(CQDs)已成为一条吸引人的研究路径。本综述全面剖析了混合掺杂CQDs的合成、特性和新兴应用,突出了它们在化学传感、生物传感、生物成像等领域的潜力,从而推动了诊断、治疗和对复杂生物过程的理解的进步。这种协同组合增强了它们对特定化学分析物的灵敏度和选择性。所形成的CQDs表现出了显著的荧光特性,可用于精确的化学传感应用。这种金属修饰的CQDs表现出从Hg到Fe和Mn离子的选择性和敏感性检测的能力。通过影响它们的卓越荧光特性,它们能够实现对尿酸、胆固醇和许多抗生素等生物分子的精确检测和监测。此外,在生物成像方面,这些掺杂的CQDs对于细胞系的检测表现出独特的行为。它们能够在广泛的光谱范围内发射光,实现高分辨率成像并减少背景噪声。我们揭示了它们在可视化不同癌细胞系方面的潜力,为癌症研究和诊断提供了宝贵的见解。总之,混合掺杂CQDs的合成为化学传感、生物传感和生物成像领域的革命性进展铺平了道路。随着我们对这一领域的深入研究,我们将解锁诊断、治疗和理解复杂生物过程的新可能性。
In nanotechnology, the synthesis of carbon quantum dots (CQDs) by mixed doping with metals and non-metals has emerged as an appealing path of investigation. This review offers comprehensive insights into the synthesis, properties, and emerging applications of mixed-doped CQDs, underlining their potential for revolutionary advancements in chemical sensing, biosensing, bioimaging, and, thereby, contributing to advancements in diagnostics, therapeutics, and the under standing of complex biological processes. This synergistic combination enhances their sensitivity and selectivity towards specific chemical analytes. The resulting CQDs exhibit remarkable fluorescence properties that can be involved in precise chemical sensing applications. These metal-modified CQDs show their ability in the selective and sensitive detection from Hg to Fe and Mn ions. By influencing their exceptional fluorescence properties, they enable precise detection and monitoring of biomolecules, such as uric acid, cholesterol, and many antibiotics. Moreover, when it comes to bioimaging, these doped CQDs show unique behavior towards detecting cell lines. Their ability to emit light across a wide spectrum enables high-resolution imaging with minimal background noise. We uncover their potential in visualizing different cancer cell lines, offering valuable insights into cancer research and diagnostics. In conclusion, the synthesis of mixed-doped CQDs opens the way for revolutionary advancements in chemical sensing, biosensing, and bioimaging. As we investigate deeper into this field, we unlock new possibilities for diagnostics, therapeutics, and understanding complex biological processes.