光动力疗法（Photodynamic therapy，PDT）是一种越来越受欢迎的皮肤治疗方法，不仅用于治疗危及生命的皮肤病和其他肿瘤，还可用于美容目的。PDT对基础功能结构几乎没有影响，使组织再生成为可能。PDT利用光敏剂（photosensitizer，PS）和可见光产生细胞毒性活性氧自由基，破坏细胞器并触发细胞死亡。现代光动力疗法的基础可以追溯到19世纪末和20世纪初，并且近年来，随着新光源和光敏剂的发展，它受到了更多关注。本综述主要关注光动力疗法在皮肤癌病变治疗中的光技术的最新进展。它讨论了近期的研究和光发射技术的发展，它们的潜在益处和缺点，以及它们对临床实践的影响。最后，本综述总结了重要发现，并讨论了它们对PDT在皮肤癌治疗中的应用的影响，突出了当前方法的局限性，并提供了改进PDT的疗效和安全性的未来研究方向的见解。本综述旨在全面了解PDT在皮肤癌治疗中的各个方面，从基本机制到该领域的最新技术进展。

Photodynamic therapy (PDT) is an increasingly popular dermatological treatment not only used for life-threatening skin conditions and other tumors but also for cosmetic purposes. PDT has negligible effects on underlying functional structures, enabling tissue regeneration feasibility. PDT uses a photosensitizer (PS) and visible light to create cytotoxic reactive oxygen species, which can damage cellular organelles and trigger cell death. The foundations of modern photodynamic therapy began in the late 19th and early 20th centuries, and in recent times, it has gained more attention due to the development of new sources and PSs. This review focuses on the latest advancements in light technology for PDT in treating skin cancer lesions. It discusses recent research and developments in light-emitting technologies, their potential benefits and drawbacks, and their implications for clinical practice. Finally, this review summarizes key findings and discusses their implications for the use of PDT in skin cancer treatment, highlighting the limitations of current approaches and providing insights into future research directions to improve both the efficacy and safety of PDT. This review aims to provide a comprehensive understanding of PDT for skin cancer treatment, covering various aspects ranging from the underlying mechanisms to the latest technological advancements in the field.