患有眼部弓形虫病的患者中白细胞介素-10（interleukin-10）水平升高。
Elevated interleukin-10 levels in patients with ocular toxoplasmosis.
发表日期：2023 Aug
作者：
Gee-Hyun Kim, Jae Hyuck Kwak, Young-Hoon Park
来源：
CYTOKINE & GROWTH FACTOR REVIEWS
摘要：
在老年患者中，眼睛弓形虫病是最常见的葡萄膜炎症病因之一，需要与眼球淋巴瘤进行鉴别诊断，后者是老年人常见的葡萄膜炎症病理学。高水平的白细胞介素(IL)-10和IL-10/IL-6比值大于1（>1.0）是诊断眼球淋巴瘤的有帮助的参数。本研究中，我们使用房水样本检测出4例具有高水平IL-10和IL-10/IL-6比值大于1的眼睛弓形虫病患者。我们的结果表明，眼睛弓形虫病可能与房水中细胞因子水平增加有关。
In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor.