本研究报告了我们在通过患者特异性骨切割导板（PSBCGs）辅助下进行广泛切除手术并随后使用3D打印个性化植入物（3DPIs）进行重建的攻击性骨盆GCT治疗中的经验，目的是介绍该方法的手术技术并评估其临床疗效。我们回顾性分析了2019年8月至2021年2月期间接受广泛切除骨盆GCT并随后重建3DPIs的七位患者。其中两名男性和五名女性，平均年龄为43岁。使用3D打印技术制备了PSBCGs和3DPIs。评估了该技术的手术结果、局部复发、放射学结果以及任何相关并发症。并根据肌骨肿瘤协会（MSTS）93功能评分评估了功能结果。平均随访时间为35.3个月（范围为28-45个月）。术中未发生并发症。所有患者均达到了负性手术切缘。术后盆腔X线片显示3DPIs与骨缺损的形状和大小相匹配。前后位、入口位和出口位盆腔X线片显示与手术计划一致的精确重建。此外，托摩幻影-岛津金属伪影消除技术（T-SMART）显示手术后三个月（范围为2-4个月）平均出现良好的骨整合。没有局部复发或肿瘤转移。最后随访时的平均MSTS评分为24.4（范围为23-27）。一名患者出现了延迟性创面愈合，经清创后伤口愈合。随访期间未检测到与假体相关的并发症，如无菌松动或结构失效。通过PSBCGs辅助广泛切除攻击性骨盆GCT并随后使用3DPIs进行重建的治疗是一种可行的方法，可以获得良好的临床结果和合理的功能结果。© 2023. BioMed Central Ltd.，Springer Nature的一部分。

This study reports our experience in the treatment of aggressive pelvic GCT through wide resection assisted with patient-specific bone-cutting guides (PSBCGs) and subsequent reconstruction with 3D-printed personalized implants (3DPIs), aiming to present the operative technique of this method and evaluate its clinical efficacy.We retrospectively analyzed seven patients who underwent wide resection of pelvic GCT followed by reconstruction with 3DPIs from August 2019 to February 2021. There were two males and five females, with a mean age of 43 years. PSBCGs and 3DPIs were prepared using 3D-printing technology. The operational outcomes, local recurrence, radiological results, and any associated complications of this technique were assessed. And the functional outcomes were assessed according to the Musculoskeletal Tumor Society (MSTS) 93 functional score.The mean follow-up time was 35.3 months (range 28-45 months). There was no intraoperative complication. Negative surgical margins were achieved in all patients. Postoperative pelvic radiographs showed that 3DPIs matched the shape and size of the bone defect. The anterior-posterior, inlet, and outlet pelvic radiograph demonstrated precise reconstruction consistent with the surgical planning. In addition, tomosynthesis-Shimadzu metal artifact reduction technology (T-SMART) showed good osseointegration at an average of three months after surgery (range 2-4 months). There was no local recurrence or tumor metastasis. The average MSTS score was 24.4 (range 23-27) at the last follow-up. Delayed wound healing was observed in one patient, and the wounds healed after debridement. Prosthesis-related complications were not detected during the follow-up, such as aseptic loosening or structure failure.The treatment of aggressive pelvic GCTs through wide resection assisted with PSBCGs and subsequent reconstruction with 3DPIs is a feasible method, which provides good clinical results and reasonable functional outcomes.© 2023. BioMed Central Ltd., part of Springer Nature.