进行高风险手术的患者出现血流动力学不稳定和并发症风险增加。然而，大多数可用数据集中在围手术期。本研究旨在利用电流计衡量技术，全面描述围手术期患者的血流动力学监测情况。在一项前瞻性、观察性、单中心的初步研究中，对30例进行多器官细胞还原手术的原发性卵巢癌患者进行了电流计衡量测量，包括手术前、手术中和住院期间的多次测量。按Clavien-Dindo分类划分严重术后并发症作为分组标准。基线到首个术中时间点的相对变化显示心率（HR）减少（中位数为-19［25分位数-26％，75分位数-10％］，p<0.0001），搏出量指数（SVI）减少（-9.5［-15.3；3.2］%，p=0.0038），心脏指数（CI）减少（-24.5［-32；-13］%，p<0.0001），收缩能力指数（-17.5［-35.3；-0.8］%，p<0.0001）。围手术期间内患者心率和心脏指数降低（p<0.0001），术后心率和心脏指数增加（p<0.0001，p=0.016）；而搏出量指数无变化。胸腔液体容量与术前相比持续增加，并且在出院当天仍未恢复正常。术后并发症患者围手术期间的收缩能力指数较低（p=0.0435），舒张时间比例较高（p=0.0008），与无并发症患者相比，心脏指数（p=0.3337）在两组之间无显著差异。由于一名患者未接受计划手术，因此被排除在数据分析之外。从术前到首个术中时间点，心率、搏出量指数、心脏指数和收缩能力指数均显著减少。围手术期间心率和心脏指数发生改变。术后并发症患者在心脏功能指标（收缩能力指数较低和搏出量指数较低）方面与无并发症患者有所不同。使用EC等无创技术对整个围手术期时间段的趋势进行分析，似乎有助于识别血流动力学参数异常的患者，并因此增加术后重大手术并发症的风险。©2023. 欧洲重症医学会和Springer Nature Switzerland AG.

Patients undergoing high-risk surgery show haemodynamic instability and an increased risk of morbidity. However, most of the available data concentrate on the intraoperative period. This study aims to characterise patients with advanced haemodynamic monitoring throughout the whole perioperative period using electrical cardiometry.In a prospective, observational, monocentric pilot study, electrical cardiometry measurements were obtained using an Osypka ICON™ monitor before surgery, during surgery, and repeatedly throughout the hospital stay for 30 patients with primary ovarian cancer undergoing multivisceral cytoreductive surgery. Severe postoperative complications according to the Clavien-Dindo classification were used as a grouping criterion.The relative change from the baseline to the first intraoperative timepoint showed a reduced heart rate (HR, median - 19 [25-quartile - 26%; 75-quartile - 10%]%, p < 0.0001), stroke volume index (SVI, - 9.5 [- 15.3; 3.2]%, p = 0.0038), cardiac index (CI, - 24.5 [- 32; - 13]%, p < 0.0001) and index of contractility (- 17.5 [- 35.3; - 0.8]%, p < 0.0001). Throughout the perioperative course, patients had intraoperatively a reduced HR and CI (both p < 0.0001) and postoperatively an increased HR (p < 0.0001) and CI (p = 0.016), whereas SVI was unchanged. Thoracic fluid volume increased continuously versus preoperative values and did not normalise up to the day of discharge. Patients having postoperative complications showed a lower index of contractility (p = 0.0435) and a higher systolic time ratio (p = 0.0008) over the perioperative course in comparison to patients without complications, whereas the CI (p = 0.3337) was comparable between groups. One patient had to be excluded from data analysis for not receiving the planned surgery.Substantial decreases in HR, SVI, CI, and index of contractility occurred from the day before surgery to the first intraoperative timepoint. HR and CI were altered throughout the perioperative course. Patients with postoperative complications differed from patients without complications in the markers of cardiac function, a lower index of contractility and a lower SVI. The analyses of trends over the whole perioperative time course by using non-invasive technologies like EC seem to be useful to identify patients with altered haemodynamic parameters and therefore at an increased risk for postoperative complications after major surgery.© 2023. European Society of Intensive Care Medicine and Springer Nature Switzerland AG.