68Ga-PSMA-11 PET/CT对前列腺腺癌孤立顶叶腹膜转移病例的应用
68Ga-PSMA-11 PET/CT in a Case of Isolated Parietal Peritoneal Metastasis From Prostate Adenocarcinoma.
发表日期：2023 Oct 01
作者：
Qian Zhao, Aisheng Dong, Changjing Zuo
来源：
CLINICAL NUCLEAR MEDICINE
摘要：
前列腺癌腹膜转移极为罕见。我们报告了一例前列腺腺癌术后35个月出现独立的腹膜壁转移的68Ga-PSMA-11 PET/CT检查结果。腹膜转移表现为多灶强烈的PSMA摄取，但68Ga-PSMA-11 PET/CT显示结构异常较为微细。患者随后接受了雄激素剥夺疗法。雄激素剥夺疗法治疗后25个月，腹膜转移进展且被手术切除。组织学和免疫组化评估显示，腹膜转移为治疗相关的神经内分泌分化的前列腺腺癌转移。该病例证明了68Ga-PSMA-11 PET/CT在识别非典型前列腺腺癌转移中的有用性。版权所有 © 2023 Wolters Kluwer Health，Inc. 保留所有权利。
Isolated peritoneal metastasis of prostate cancer is extremely rare. We present 68Ga-PSMA-11 PET/CT findings in a case of isolated parietal peritoneal metastasis from prostate adenocarcinoma 35 months after radical prostatectomy. The peritoneal metastases showed multifocal intense PSMA uptake, but subtle structural abnormalities on 68Ga-PSMA-11 PET/CT. The patient was subsequently treated with androgen deprivation therapy. The peritoneal metastases progressed 25 months after the initiation of androgen deprivation therapy and were removed surgically. Histologic and immunohistochemical evaluation revealed metastatic prostate adenocarcinoma with treatment-related neuroendocrine differentiation. This case demonstrates the usefulness of 68Ga-PSMA-11 PET/CT in identifying atypical metastasis from prostate adenocarcinoma.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.