使用最新一代CZT相机记录的快速全身层析扫描图像，对于177Lu-PSMA治疗的监测起到了重要作用。
177Lu-PSMA Treatment Monitoring Through Serial Fast Whole-Body Tomoscintigraphies Recorded With a Latest-Generation CZT-Camera.
发表日期：2023 Oct 01
作者：
Caroline Boursier, Pierre Olivier, Marine Claudin, Pierre-Yves Marie, Laetitia Imbert
来源：
CLINICAL NUCLEAR MEDICINE
摘要：
用177Lu-前列腺特异性膜抗原（PSMA）治疗的正电子发射计算机断层扫描（tomoscintigraphy）监测可能有助于质量控制和预测治疗反应。此外，新的CZT-摄像机可以克服相对较低的图像质量和较长的记录时间的缺点，提供快速、高质量的全身记录。尽管仍需要进一步的大规模验证，但当前的病例报告表明，这些CZT-摄像机有潜力提供直观而全面的177Lu-PSMA治疗监测，即<20分钟的全身正电子发射计算机断层扫描记录、肿瘤活动与68Ga-PSMA PET相一致，无需任何额外的示踪剂注射。版权所有© 2023 Wolters Kluwer Health, Inc. 保留所有权利。
The tomoscintigraphy monitoring of 177Lu-prostate-specific membrane antigen (PSMA) treatment may be helpful for quality control and predicting therapeutic response. Furthermore, the drawbacks of relatively low image quality and extended recording times can be overcome by new CZT-cameras providing fast, high-quality, whole-body recordings. Although still requiring further larger-scale confirmation, the current case report demonstrates that these CZT-cameras have the potential to provide straightforward and comprehensive 177Lu-PSMA treatment monitoring, that is, <20-minute whole-body tomoscintigraphy recording, tumor activities concordant with those from 68Ga-PSMA PET, and no requirement for any additional tracer injection.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.