卵巢癌（OC）被描述为一种异质且复杂的疾病，具有较高的死亡率、弱预后和晚期表现。OC根据不同指标（例如起源和组织病理学）有几个亚组。当前针对OC的治疗方法包括手术后的化疗和放疗，然而，这些方法在OC上表现出多样化的副作用，并且没有足够的有效性。最近，基于间充质干细胞（MSC）的治疗在治疗癌症等多种问题上备受关注。这些多能干细胞可以从不同来源（如脐带、脂肪组织、骨髓和胎盘）中获取，并已针对OC进行了研究其疗效。因此，在这篇综述中，我们旨在回顾和讨论关于不同来源的MSC对OC的影响的现有研究，特别关注所涉及的机制。© 2023 Wiley Periodicals LLC.

Ovarian cancer (OC) is described as a heterogeneous complex condition with high mortality, weak prognosis, and late-stage presentation. OC has several subgroups based on different indices, like the origin and histopathology. The current treatments against OC include surgery followed by chemotherapy and radiotherapy; however, these methods have represented diverse side effects without enough effectiveness on OC. Recently, mesenchymal stem cell (MSC)-based therapy has acquired particular attention for treating diverse problems, such as cancer. These multipotent stem cells can be obtained from different sources, such as the umbilical cord, adipose tissues, bone marrow, and placenta, and their efficacy has been investigated against OC. Hence, in this narrative review, we aimed to review and discuss the present studies about the effects of various sources of MSCs on OC with a special focus on involved mechanisms.© 2023 Wiley Periodicals LLC.