深静脉血栓形成患者应用下腔静脉滤器和导管直接溶栓治疗与住院回诊相关性的研究。
Association of Vena Cava Filters And Catheter-Directed Thrombolysis for Deep Vein Thrombosis with Hospital Readmissions.
发表日期:2023 Sep 09
作者:
Irfan Shafi, Brooke Zlotshewer, Matthew Zhao, Vladimir Lakhter, Behnood Bikdeli, Anthony Comerota, Huaqing Zhao, Riyaz Bashir
来源:
HEART & LUNG
摘要:
美国每年约有35万名患者患上急性深静脉血栓形成(DVT)。目前对急性DVT的再入院率和预测因素的研究还不够完善。本研究旨在评估与CDT和腔静脉滤器在近端和股块DVT患者中的成因30天全因素再入院率的相关性。
我们使用2016年至2017年的全国再入院数据库评估急性近端下肢DVT的不计划再入院率,观察期为30天。我们利用Cox比例风险模型确定30天再入院率的预测因素及其与IVC过滤器和CDT的关联。共鉴定到58306名成年患者,他们有急性近端DVT的入院记录。无计划再入院率为14.7%(95%可信区间[CI]: 14.5-15.0%)。4995名(10.0%)患者接受了CDT治疗,6085名(12.2%)患者行IVC滤器置入。多变量分析结果显示,只有CDT与较低的再入院风险相关(HR 0.77,95% CI 0.71-0.84,p<0.001),而IVC过滤器置入(HR 1.26,95% CI 1.19-1.34,p<0.001)、Charlson指数>3(HR 1.47,95% CI 1.38-1.56,p<0.001)、恶性肿瘤(HR 1.45,95% CI 1.34-1.57,p<0.001)和住院时间超过5天(HR 1.39,95%CI 1.33-1.46,p<0.001)、AKI(HR 1.18,95%CI 1.11-1.25,p<0.001)与更高的再入院率相关。
急性近端DVT患者的30天不计划再入院率仍然很高。CDT与较低的再入院率相关,而IVC过滤器置入与再入院率增加相关。
版权所有 © 2023. Elsevier Inc. 发表
Acute deep vein thrombosis (DVT) affects more than 350,000 patients each year in the United States. Contemporary rehospitalization rates and predictors of acute DVT have not been well characterized. We aimed to evaluate the all-cause 30 days readmission rate and its association with CDT and vena cava filters in patients with proximal and caval DVT.Patients with index hospitalization for acute proximal lower extremity DVT were evaluated for unplanned readmission rates at 30 days using Nationwide Readmission Database from 2016 to 2017. We used Cox proportional hazard model to determine the predictors of 30-days readmissions and its association with IVC filter and CDT use.58,306 adult patients were identified with an index hospitalization for acute proximal DVT. The unplanned 30-day rehospitalization rate was 14.7% (95% confidence interval [CI]: 14.5-15.0%). 4,995 (10.0%) patients had CDT and 6,085 (12.2%) patients underwent IVC filter placement. In multivariable analysis, only CDT was associated with a lower hazard for rehospitalization (HR 0.77,95% CI 0.71-0.84, p<0.001), whereas, IVC filter placement (HR 1.26, 95% CI 1.19-1.34, p<0.001), charlson index >3 (1.47, 95% CI 1.38-1.56, p<0.001), malignancy (HR 1.45, 95% CI 1.34-1.57, p<0.001), and length of stay more than 5 days (HR 1.39, 95% CI 1.33-1.46, p<0.001), AKI (HR 1.18, 95% CI 1.11-1.25, p<0.001)were associated with higher readmission rates.The 30-day unplanned rehospitalization rate continues to be high in patients with acute proximal DVT. CDT was associated with lower rehospitalization rates, while IVC filter placement was associated with increased rehospitalization rates.Copyright © 2023. Published by Elsevier Inc.