Kachri（Cucumis callosus）是一种被较少开发利用的葫芦科植物果实，主要分布在印度的哈里亚纳邦、拉贾斯坦邦和古吉拉特邦的干旱地区。本地人传统上以家庭级的加工方式小规模使用该果实。Kachri是一种多年生草本植物，已被证明具有治疗某些疾病的潜力。在几项研究中，已报道了Kachri具有抗氧化、抗高脂血症、抗糖尿病、抗癌、抗微生物和心脏保护等特性。该果实在蛋白质、碳水化合物、必需脂肪酸、酚类和各种植物化学物质方面具有良好的营养价值。此外，对该作物进行了伽马辐射处理以减少总细菌计数（TBC），确保在果实及其产品的储存期间免受病原体污染。这些事实为从这种功能丰富的作物中开发功能性食品和药用价值的医学食品提供了基础。将传统有价值的干旱地区食品加工成功能性食品和产品可以潜在地提高全球人民的生计和营养安全。因此，本综述关注Kachri果实在非传染性疾病（NCDs）管理，特别是糖尿病、癌症和高脂血症方面的治疗和药理潜力。综述的图形摘要。©2023年作者（们），在Springer Science+Business Media, LLC和Springer Nature的独家许可下。

Cucumis callosus (Kachri) is an under-exploited fruit of the Cucurbitaceae family, distributed majorly in the arid regions of India in the states of Haryana, Rajasthan, and Gujarat. The fruit is traditionally used by the native people at a small scale by home-level processing. It is a perennial herb that has been shown to possess therapeutic potential in certain disorders. In several studies, the antioxidant, anti-hyperlipidaemic, anti-diabetic, anti-cancerous, anti-microbial, and cardioprotective properties of Kachri have been reported. The fruit has a good nutritional value in terms of high percentages of protein, carbohydrates, essential fatty acids, phenols, and various phytochemicals. Also, gamma radiation treatment has been used on this crop to reduce total bacterial counts (TBC), ensuring safety from pathogens during the storage period of the fruit and its products. These facts lay down a foundation for the development of functional food formulations and nutraceuticals of medicinal value from this functionally rich crop. Processing of traditionally valuable arid region foods into functional foods and products can potentially increase the livelihood and nutritional security of people globally. Therefore, this review focuses on the therapeutic and pharmacological potentials of the Kachri fruit in the management of non-communicable diseases (NCDs) namely, diabetes, cancer, and hyperlipidemia. Graphical abstract of the review.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.