该荟萃分析旨在评估运动干预对超重/肥胖的乳腺癌幸存者的身体组成和生活质量的影响。资格符合要求的随机对照试验(RCTs)从科克兰图书馆、PubMed和Embase数据库中搜索，并使用科克兰协作组的风险评估工具进行评估。效应量以加权平均差(WMD)的形式进行汇总，用于身体组成变量(如体质指数[BMI]、脂肪含量、体重、脂肪质量、瘦体质量、骨密度)和生活质量(如身体健康和心理健康)，并将置信区间(CI)设置为95%。由于存在异质性，进行亚组分析以检测异质性来源。 分析包括了来自6个RCTs的8篇文章，共计548名超重/肥胖的乳腺癌幸存者(BMI ≥ 25 kg/m2)。与常规护理相比，运动干预显著降低了超重/肥胖的乳腺癌幸存者的体质指数[WMD(95% CI) = -1.37 (-2.50, -0.23) kg/m2]和体脂肪[WMD(95% CI) = -3.80 (-6.59, -1.01) %]。运动干预显示了增加身体健康[WMD(95% CI) = 2.65 (-10.19, 15.48)]和心理健康[WMD(95%CI) = 1.38 (-4.18, 6.95)]的趋势，但没有观察到统计学显著性。亚组分析显示干预持续时间是影响身体组成的异质性来源。在16周的亚组中，运动干预降低了脂肪质量和BMI，同时增加了瘦体质量和骨密度。52周的运动干预在增加瘦体质量方面效果显著。只在12周的亚组中检测到减少脂肪质量的显著运动干预效应。 运动干预明显降低了超重/肥胖的乳腺癌幸存者的体质指数和体脂肪。对超重/肥胖的乳腺癌幸存者进行运动干预的益处需要来自高质量RCTs的更多证据，并具备较大样本量。 © 2023. BioMed Central有限公司，施普林格自然出版集团的一部分。

This meta-analysis aimed to assess the effects of exercise interventions on body composition and quality of life in overweight/obese breast cancer survivors.Eligible randomized controlled trials (RCTs) were searched from the Cochrane Library, PubMed, and Embase databases and assessed using the Cochrane Collaboration's assessing risk tool. The effect size was pooled as weighted mean difference (WMD) for body composition variables (i.e., body mass index [BMI], body fat, body weight, fat mass, lean mass, bone mineral density) and quality of life (i.e., physical health and mental health), and the confidence interval (CI) was set as 95%. Since heterogeneity existed, subgroup analysis was conducted to detect the source of heterogeneity.Eight articles from six RCTs containing 548 overweight/obese breast cancer survivors (BMI ≥ 25 kg/m2) were included and analyzed. Compared to routine care, exercise intervention significantly decreased the body mass index [WMD (95% CI) = -1.37 (-2.50, -0.23) kg/m2] and body fat [WMD (95% CI) = -3.80 (-6.59, -1.01) %] of overweight/obese breast cancer survivors. Exercise intervention showed a tendency to increase physical health [WMD (95% CI) = 2.65 (-10.19, 15.48)] and mental health [WMD (95%CI) = 1.38 (-4.18, 6.95)], but no statistical significance was observed. A subgroup analysis showed the duration of intervention was a source of heterogeneity on body composition. In the 16-week subgroup, exercise intervention decreased fat mass and BMI while increased lean mass and bone mineral density. The 52-week exercise intervention was effective in increasing lean mass. A significant exercise intervention effect on reducing body fat was only detected in the 12-week subgroup.Exercise intervention significantly decreased the body mass index and body fat of overweight/obese breast cancer survivors. The benefits of exercise interventions for overweight/obese breast cancer survivors need more evidence from high-quality RCTs with large sample sizes.© 2023. BioMed Central Ltd., part of Springer Nature.