火凤凰是一种细胞死亡方式，其特点是细胞的破坏，对免疫系统和癌症免疫治疗有重要影响。破坏素家族负责激活火凤凰，其中包括细胞膜形成孔隙以允许炎症因子的释放。炎症体反应是一种强大的机制，在细胞损伤发生时有助于消除细菌和癌细胞。随着肿瘤细胞对凋亡的抵抗力增强，癌症的其他治疗方法变得更加受欢迎。全面了解火凤凰对于将其用于癌症治疗至关重要，考虑到火凤凰与免疫系统对肿瘤的防御反应之间的复杂关联。本综述提供了火凤凰机制、破坏素家族与火凤凰的关系以及火凤凰与抗肿瘤免疫之间的相互作用的概述。此外，还讨论了火凤凰在癌症免疫治疗中的潜在意义。此外，我们还探讨了未来的研究可能性，并介绍了一种新的肿瘤治疗方法。© 作者。

Pyroptosis is a form of cell death that is characterized by the destruction of the cell, and it has implications in both the immune system and cancer immunotherapy. The gasdermin family is responsible for the activation of pyroptosis, which involves the formation of pores in the cellular membrane that permit the discharge of inflammatory factors. The inflammasome response is a powerful mechanism that helps to eliminate bacteria and cancer cells when cellular damage occurs. As tumor cells become more resilient to apoptosis, other treatments for cancer are becoming more popular. It is essential to gain a thorough understanding of pyroptosis in order to use it in cancer treatment, considering the intricate association between pyroptosis and the immune system's defensive reaction against tumors. This review offers an overview of the mechanisms of pyroptosis, the relationship between the gasdermin family and pyroptosis, and the interplay between pyroptosis and anti-tumor immunity. In addition, the potential implications of pyroptosis in cancer immunotherapy are discussed. Additionally, we explore future research possibilities and introduce a novel approach to tumor treatment.© The author(s).