通过在美国的Surveillance, Epidemiology, and End results (SEER)数据库中研究社会经济地位（SES）与美国盲肠腺癌患者的疾病死亡率的关系。从2011年至2015年，查询SEER数据库找出诊断为盲肠腺癌的患者。使用因子分析、聚类分析、以及单变量和多变量Cox比例风险模型进行数据分析。共鉴定出五个社会保障因素：因素1为经济和教育劣势；因素2为与移民相关的特征（语言孤立和外国出生）；因素3为县内流动率高；因素4为州内流动率高；因素5为国内流动率高。基于SES的五个群集被明确的鉴定出来。所有原因死亡数在17,185名患者中为5948人，幸存者数为11,237人。在多变量Cox回归分析中，以群集1（低贫困率和高教育水平）作为参考，群集3（县内流动率高）的风险比（HR）为1.13（95％CI：1.04-1.21，P <0.05），比群集1的风险高13％。群集4（低语言孤立，外国出生，住房过度拥挤和国内流动率低）的HR为1.15（95％CI：1.07-1.24，P <0.001），比群集1的风险高15％。群集5（经济和教育劣势，与移民相关的特征和国内流动率低）的HR为1.11（95％CI：1.03-1.20，P <0.01），比群集1的风险高11％。与社会经济地位指标相关的因素基于盲肠腺癌患者的死亡率，表明低经济和教育水平是盲肠腺癌的危险因素。低社会经济地位与美国盲肠腺癌患者的死亡风险增加相关，并显示出不同的分布模式，依赖于人群。改善健康保险政策和加强心理治疗可以为改善盲肠腺癌患者的预后提供指导。

To explore the relationship between socioeconomic status (SES) and disease mortality in patients with cecal adenocarcinoma in America through the Surveillance, Epidemiology, and End results (SEER) database.The SEER database was queried for patients with cecal adenocarcinoma in America diagnosed from 2011 to 2015. Factor analysis, cluster analysis, and univariate and multivariate Cox proportional hazard models were used for data analysis. Five social security factors were identified: factor 1, economic and educational disadvantage; factor 2, characteristics related to immigration (language isolation and foreign birth); factor 3, high relocation rate in the county; factor 4, high intra-state relocation rate; and factor 5, high domestic relocation rate. Five clusters defined by SES were identified.The number of all-cause deaths among 17 185 patients was 5948, and the number of survivors was 11, 237. In the multivariate Cox regression analysis, with cluster 1 (low poverty rate and high education level) as the reference, the hazard ratio (HR) of cluster 3 (high intra-county mobility rate) was 1.13 (95% CI: 1.04-1.21, P < 0.05), and the risk was 13% higher than that of cluster 1. The HR of cluster 4 (low language isolation, foreign birth, housing overcrowding, and intra-country mobility rates) was 1.15 (95% CI: 1.07- 1.24, P < 0.001) with a 15% higher risk than cluster 1. The HR of cluster 5 (economic and educational disadvantages, immigration-related characteristics, and low intra-country mobility) was 1.11 (95% CI: 1.03-1.20, P < 0.01) with a 11% higher risk. The factors related to SES indicators were based on the mortality of patients with cecal adenocarcinoma, indicating that low economic and education levels are risk factors for cecal adenocarcinoma.Low socioeconomic status is associated with an increased risk of death in patients with cecal adenocarcinoma in the United States and show different distribution patterns based on population. Improving health insurance policies and strengthening psychotherapy can provide guidance for improving prognosis f cecal adenocarcinoma patients.