口腔有不同种类的良性和恶性病变。临床上，只有进行充分的手术活检和随后的组织病理学检查才能明确诊断。活检技术不足、活检位置选择不当、组织处理和患者信息记录不当可能会导致口腔病理学家出现伪影和误诊。软组织稳定是口腔手术过程中的一个挑战。需要操作者、助手和患者的通力合作，克服困难，确保成功。在本文中，我们回顾了临床手术活检的程序，并提出了三种当前的组织稳定方法，包括手指和纱布稳定、霰粒肿钳和适配器械稳定以及回缩缝线稳定。此外，还提出了一些限制。临床医生应根据口腔病变的临床特点、周围的解剖结构以及自己的临床经验和偏好来选择合适的工具。对这些活检和组织稳定方法的更多了解可以有效改进活检程序并获得足够的组织进行组织病理学检查并随后出具准确的病理报告。© 2023 中华民国牙科科学协会。 Elsevier B.V. 的出版服务

There are different kinds of benign and malignant lesions in the oral cavity. Clinically, definite diagnosis can be confirmed only by doing adequate surgical biopsy and subsequent histopathological examination. Inadequate biopsy technique, unsuitable selection of the location for biopsy, inappropriate tissue handling and record of patients' information may lead to artifacts and misdiagnosis by the oral pathologists. Soft tissue stabilization is a challenge during oral surgery procedures. It needs the cooperation of operator, assistants, and patients to overcome the difficulty and ensure the successful outcome. In this article, we reviewed the procedures for clinical surgical biopsy, and raised three current tissue stabilization methods including fingers and gauze stabilization, stabilization with chalazion forceps and adapted instruments, and stabilization with retraction sutures. Moreover, some limitations were also presented. Clinician should examine the clinical characteristics of the oral lesion, the surrounding anatomical structures, and their own clinical experience and preference to select the appropriate tool. More understanding of these biopsy and tissue stabilization methods can effectively improve the biopsy procedures and obtain adequate tissues for histopathological examination and subsequent issue of an accurate pathological report.© 2023 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.