研究动态
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针对老年妇女关于停止乳腺癌筛查邀请的信息的随机试验。

Randomized Trial of Information for Older Women About Cessation of Breast Cancer Screening Invitations.

发表日期:2024 Feb 26
作者: Jenna Smith, Erin Cvejic, Nehmat Houssami, Mara A Schonberg, Wendy Vincent, Vasi Naganathan, Jesse Jansen, Rachael H Dodd, Katharine Wallis, Kirsten J McCaffery
来源: JOURNAL OF GENERAL INTERNAL MEDICINE

摘要:

老年女性没有收到任何有关澳大利亚乳房筛查计划 (BreastScreen) 邀请为何在 74 年后停止的信息。我们测试了向老年女性提供停止乳腺筛查的理由如何影响知情选择(充分的知识;筛查态度与意图一致)。在一项三组在线随机试验中,符合条件的参与者是年龄在 70-74 岁之间、最近参加过乳腺癌筛查的女性。通过 Qualtrics 招募无个人乳腺癌病史的乳房筛查(5 年内)。参与者阅读了一个假设场景,其中他们收到了一封BreastScreen信函,报告其乳房X光检查没有异常。他们被随机接收这封信:(1)没有任何停止筛查的理由(对照); (2) 以印刷文本形式说明停止筛查的理由(例如,74 岁以后筛查的弊大于利); (3) 以动画视频形式呈现停止放映的理由。主要结局是 74 岁以后关于继续/停止乳房筛查的明智选择。总共分析了 376 名参与者的反应。与对照组 (n = 122) 相比,干预组参与者(文本 [n = 132] 或动画 [n = 122])更有可能做出明智的选择(对照 18.0%;文本 32.6%,p = .010;动画40.5%,p< .001)。干预组参与者拥有更充分的知识(对照 23.8%;文本 59.8%,p < .001;动画 68.9%,p< .001),筛选意图较低(对照 17.2%;文本 36.4%,p< .001;动画 49.2 %,p < .001),动画组中对自身筛选的积极筛选态度较少,但文本组中则不然(对照 65.6%;文本 51.5%,p = .023;动画 40.2%,p < .001 ).向老年妇女提供有关停止乳腺癌筛查的基本原理的信息可以增加假设情况下的知情决策。这项研究是改善国家癌症筛查提供者直接向老年人提供的信息传递的重要第一步。需要进一步研究来评估干预措施不同要素的影响以及在临床实践中提供此信息的影响,并使用更多样的样本。ANZCTRN12623000033640.© 2024。作者。
Older women receive no information about why Australia's breast screening program (BreastScreen) invitations cease after 74 years. We tested how providing older women with the rationale for breast screening cessation impacted informed choice (adequate knowledge; screening attitudes aligned with intention).In a three-arm online randomized trial, eligible participants were females aged 70-74 years who had recently participated in breast screening (within 5 years), without personal breast cancer history, recruited through Qualtrics. Participants read a hypothetical scenario in which they received a BreastScreen letter reporting no abnormalities on their mammogram. They were randomized to receive the letter: (1) without any rationale for screening cessation (control); (2) with screening cessation rationale in printed-text form (e.g., downsides of screening outweigh the benefits after age 74); or (3) with screening cessation rationale presented in an animation video form. The primary outcome was informed choice about continuing/stopping breast screening beyond 74 years.A total of 376 participant responses were analyzed. Compared to controls (n = 122), intervention arm participants (text [n = 132] or animation [n = 122]) were more likely to make an informed choice (control 18.0%; text 32.6%, p = .010; animation 40.5%, p < .001). Intervention arm participants had more adequate knowledge (control 23.8%; text 59.8%, p < .001; animation 68.9%, p < .001), lower screening intentions (control 17.2%; text 36.4%, p < .001; animation 49.2%, p < .001), and fewer positive screening attitudes regarding screening for themselves in the animation arm, but not in the text arm (control 65.6%; text 51.5%, p = .023; animation 40.2%, p < .001).Providing information to older women about the rationale for breast cancer screening cessation increased informed decision-making in a hypothetical scenario. This study is an important first step in improving messaging provided by national cancer screening providers direct to older adults. Further research is needed to assess the impact of different elements of the intervention and the impact of providing this information in clinical practice, with more diverse samples.ANZCTRN12623000033640.© 2024. The Author(s).