本研究比较了早期宫颈癌患者接受开腹根治性子宫切除术（LRH）和微创根治性子宫切除术（MISRH）的结果。接受LRH或MISRH（腹腔镜/机器人）的早期宫颈癌患者的临床数据回顾性分析长庚医院林口分院2002年至2017年的临床情况。分析手术安全性（手术时间、失血量、输血率、术后住院时间和围手术期并发症）、总生存期（OS）、无病生存期（DFS）和复发模式。以 3:1 的比例进行倾向评分匹配 (PSM)，以平衡预后变量。在 760 名患者（整个队列）中，614 名患者接受了 LRH，146 名患者接受了 MISRH。 PSM 后，LRH 组和 MISRH 组分别包括 394 名和 140 名患者。 MISRH 组的 5 年 OS 率显着低于 LRH 组（85.6% vs. 93.2%，p=0.043），而 5 年 DFS 率（p=0.21）没有显着差异。 PSM 后，MISRH 和 LRH 组之间的 5 年 OS 率没有显着差异（87.1% vs. 92.1%，p=0.393）。 MISRH 组的手术时间显着缩短（p<0.001），术中失血量较低（p<0.001），输血率较低（p<0.001），术后停留时间较短（p<0.001），但术后住院时间显着较高。术中膀胱损伤 (p<0.001) 高于 LRH 组。PSM 后，MISRH 与 OS 显着降低相关，但术中泌尿系统并发症的风险显着高于 LRH。© 2024。亚洲妇科肿瘤学会、韩国妇科肿瘤学会，和日本妇科肿瘤学会。

This study compared the outcomes of laparotomic radical hysterectomy (LRH) and minimally invasive radical hysterectomy (MISRH) in patients with early-stage cervical cancer.The clinical data of patients with early-stage cervical cancer who underwent LRH or MISRH (laparoscopic/robotic) at Chang Gung Memorial Hospital, Linkou Branch, from 2002 to 2017 were retrospectively reviewed. The surgical safety (operation time, blood loss, blood transfusion rate, length of postoperative stay, and perioperative complications), overall survival (OS), disease-free survival (DFS), and recurrence pattern were analyzed. Propensity score matching (PSM) at a 3:1 ratio was performed to balance prognostic variables.Of the 760 patients (entire cohort), 614 underwent LRH and 146 underwent MISRH. After PSM, 394 and 140 patients were included in the LRH and MISRH groups, respectively. The 5-year OS rate was significantly lower in the MISRH group than in the LRH group (85.6% vs. 93.2%, p=0.043), and the 5-year DFS rate (p=0.21) did not differ significantly. After PSM, the 5-year OS rates did not differ significantly between the MISRH and LRH groups (87.1% vs. 92.1%, p=0.393). The MISRH group had a significantly shorter operation time (p<0.001), lower intraoperative blood loss (p<0.001), lower blood transfusion rate (p<0.001), and shorter postoperative stay (p<0.001) but a significantly higher rate of intraoperative bladder injury (p<0.001) than the LRH group.After PSM, MISRH is associated with nonsignificantly lower OS but a significantly higher risk of intraoperative urological complications than LRH.© 2024. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology, and Japan Society of Gynecologic Oncology.