分析临床病理预后因素对 GBC OSCC 患者生存的影响。评估影响较低 GBC OSCC 患者 3 年和 5 年总生存期 (OS) 和疾病特异性生存期 (DSS) 的各种临床病理学和治疗因素之间的关联。机构伦理委员会 (IEC) 批准了回顾性研究进行了图表审核。纳入2010年至2019年经活检证实的牙龈颊复合体鳞状细胞癌（GBC OSCC）患者，这些患者主要接受手术治疗，有或没有辅助治疗，具有完整的临床病理学和随访数据。生存结果包括 2 年、3 年

To analyze the impact of clinico-pathological prognostic factors on survival in patients with GBC OSCC. To evaluate the association between various clino-pathological and treatment factors influencing the 3-year and 5-year Overall survival (OS), and Disease specific survival (DSS) in patients with lower GBC OSCC.An Institutional Ethical Committee (IEC) approved retrospective chart audit was performed. Biopsy proven squamous cell cancer of gingivobuccal complex (GBC OSCC) patients from 2010 to 2019 who were treated primarily with surgery with or without adjuvant therapy having complete clinicopathological and follow up data were included. Survival outcomes including 2-year, 3-year & 5-year OS, and DSS were calculated and analyzed. A multivariate analysis was performed to identify significant predictor for the survival outcomes. A p-value < 0.05 was considered significant.183 patients with primary OSCC were identified out of which 83 patients comprised of OSCC of lower GBC. Age (p < 0.001), tumor grade (p = 0.009), pN status (p = 0.002), PNI (p < 0.001), lymph node metastasis (p = 0.002), treatment given (p = 0.02) and adjuvant therapy (p = 0.02) were found as a significant prognostic factor in univariate analysis.The OS & DSS of the patients with lower GBC SCC is 78.3%. The 2-year, 3-year, and 5-year OS of the study population was reported to be 95.2%, 87.9%, and 78.8% respectively. PNI & lymph node metastasis were significant prognostic factor for OS with an adjusted hazard ratio 4.91 and 7.75 respectively.Copyright © 2024 Elsevier Ltd. All rights reserved.