一名 67 岁女性胸膜肿块接受 18F-FDG PET/CT，疑似恶性胸膜肿瘤，18F-FDG 强烈摄取。然后她接受了 68Ga-DOTA-FAPI-04 PET/CT 进行分期，结果显示胸膜病变的摄取相似，而纵隔和肺门淋巴结的摄取模式相反。最终，经组织病理学诊断，她患有梭形细胞肉瘤（G2）。 1个周期化疗后，胸膜病变进展，纵隔淋巴结缩小。半个月后，患者因病情进展过快而死亡。该病例表明 68Ga-FAPI PET/CT 可能成为胸膜梭形细胞肉瘤诊断和分期的一种有前途的新工具。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

A 67-year-old woman with pleural mass underwent 18F-FDG PET/CT, suspected of malignant pleural tumor with intense 18F-FDG uptake. Then she underwent 68Ga-DOTA-FAPI-04 PET/CT for staging, which showed similar uptake in pleural lesions and opposite uptake pattern in mediastinal and hilar lymph nodes. Finally, she was diagnosed with spindle cell sarcoma (G2) by histopathology. After 1 cycle chemotherapy, the pleural lesions progressed, while mediastinal lymph nodes shrunk. Half a month later, the patient died due to rapid disease progression. This case indicates that 68Ga-FAPI PET/CT might be a promising new tool in diagnosis and staging of pleural spindle cell sarcoma.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.