单个患者脑部病变的三重肿瘤(神经内分泌肿瘤、神经鞘瘤和甲状腺乳头状癌)在 68Ga-DOTATATE PET/CT 上表现出亲和性,并通过 FDG-PET/CT 和脑 MRI 进行表征。
Triple Tumors (Neuroendocrine Tumor, Schwannoma, and Papillary Thyroid Carcinoma) With Brain Lesions in a Single Patient Demonstrating Avidity on 68Ga-DOTATATE PET/CT and Their Characterization With FDG-PET/CT and Brain MRI.
发表日期:2024 May 23
作者:
Rahul V Parghane, Sandip Basu
来源:
CLINICAL NUCLEAR MEDICINE
摘要:
神经内分泌肿瘤 (NET) 通常会扩散到肝脏、淋巴结、肺部和骨骼。 NET 中的脑转移并不常见。因此,NET 中检测到的每个脑转移病例对于制定此类肿瘤的治疗指南至关重要。我们介绍了一名患者的三重肿瘤(NET、乳头状甲状腺癌和神经鞘瘤)的独特病例,该患者在 68Ga-DOTATATE-PET/CT 扫描中出现神经系统症状和生长抑素受体强烈的 T2 高信号多发性 NET 转移性脑病变,并且脑部核磁共振成像。尽管 NET 中脑转移很少见,但我们得出的结论是,NET 患者出现神经体征或症状和/或检测到生长抑素受体旺盛的脑部病变应引起对脑转移的怀疑。版权所有 © 2024 Wolters Kluwer Health, Inc 。 版权所有。
Neuroendocrine tumor (NET) typically spreads to the liver, lymph nodes, lungs, and skeleton. Brain metastasis in NET is uncommon. Therefore, each case of detected brain metastases in NET is crucial for the development of treatment guidelines for these types of tumors. We present a unique case of triple tumors (NET, papillary thyroid carcinoma, and schwannoma) in a single patient who presented with neurological symptoms and somatostatin receptor-avid T2 hyperintense multiple metastatic brain lesions from NET on 68Ga-DOTATATE-PET/CT scan and brain MRI. Despite the rarity of brain metastases in NET, we conclude that the presence of neurological sign or symptoms and/or the detection of somatostatin receptor-avid brain lesions in patients with NET should raise suspicion of brain metastases.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.