乳腺癌是全球女性中最常见的恶性肿瘤，其受 Wnt/β-catenin 信号通路的显着影响，在乳腺癌的发生和进展中发挥着至关重要的作用。虽然传统的化疗作为临床标准治疗方法存在严重的副作用、高毒性和有限的预后疗效等显着缺点，但中药（TCM）提供了一种有前途的替代方案。中医采用多靶点治疗方法，副作用较少，并提供有效治疗的巨大潜力。本文详细分析了中医药对不同亚型乳腺癌的治疗作用，重点关注其与 Wnt/β-catenin 信号通路的相互作用。此外，它还探讨了单体和复合形式的中药在乳腺癌治疗中的有效性。我们还讨论了基于 Wnt/β-catenin 信号通路中的关键蛋白建立乳腺癌治疗生物标志物的潜力。我们的目标是为乳腺癌的预防和治疗提供新的见解，并为中医标准化做出贡献。版权所有 © 2024 Li、Li、Zhang、Zhao、Ge、Sun、Fu 和 Li。

Breast cancer, the most prevalent malignant tumor among women globally, is significantly influenced by the Wnt/β-catenin signaling pathway, which plays a crucial role in its initiation and progression. While conventional chemotherapy, the standard clinical treatment, suffers from significant drawbacks like severe side effects, high toxicity, and limited prognostic efficacy, Traditional Chinese Medicine (TCM) provides a promising alternative. TCM employs a multi-targeted therapeutic approach, which results in fewer side effects and offers a high potential for effective treatment. This paper presents a detailed analysis of the therapeutic impacts of TCM on various subtypes of breast cancer, focusing on its interaction with the Wnt/β-catenin signaling pathway. Additionally, it explores the effectiveness of both monomeric and compound forms of TCM in the management of breast cancer. We also discuss the potential of establishing biomarkers for breast cancer treatment based on key proteins within the Wnt/β-catenin signaling pathway. Our aim is to offer new insights into the prevention and treatment of breast cancer and to contribute to the standardization of TCM.Copyright © 2024 Li, Li, Zhang, Zhao, Ge, Sun, Fu and Li.