研究动态
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鸭跖草属:关注分布、形态、传统药用、植物化学和民族药理学活动:更新的文献综述。

The genus Commelina: Focus on distribution, morphology, traditional medicinal uses, phytochemistry, and Ethno-pharmacological activities: An updated literature review.

发表日期:2024 May 30
作者: Abebe Dagne, Wubetu Yihunie, Getinet Nibret, Bantayehu Addis Tegegne
来源: ANTIOXIDANTS & REDOX SIGNALING

摘要:

由于新的药理学发现,天然植物药物越来越受欢迎,取代了人工模型和化学品。草本药物(如鸭跖草)越来越受欢迎和被接受,源于人们认为全天然产品是安全、容易获得和便宜的。鸭跖草属(Commelinaceae)有 200 多种,长期以来在世界各地被用来治疗各种疾病和病症。然而,据作者所知,尚无关于鸭跖草属许多具有药用价值的重要物种的综合科学报告。当前的叙述性评论旨在提供对鸭跖草各种物种的最新概述,重点关注其形态;地理分布;传统医药用途(物种类型、使用的植物部位、作用方式、治疗的疾病以及实行的国家);植物化学成分;和药理特性。数据搜索方法是利用英语电子数据库进行的,例如 PubMed、Web of Science、Scopus、Science Direct、Research Gates、Ethnobotany Research and Applications 和 Google Scholar。使用诸如“药用植物”、“鸭跖草属”、“鸭跖草物种的传统药用用途”、“鸭跖草物种的光化学”和“鸭跖草物种的药理(生物)活性”等关键术语进行了大量搜索和深入讨论实施。研究发现,许多鸭跖草属植物含有多种结构的生物活性植物化学物质(次生代谢物),包括生物碱、酚类、黄酮类、苷类、单宁、皂苷、甾醇、花青素以及其他被认为具有药理活性的物质。根据体外和临床前报告,鸭跖草物种显示出抗糖尿病、抗氧化、抗菌、镇痛、抗炎、抗癌、保肝、利尿、诱导生育、抗腹泻和驱虫活性、镇静和抗焦虑活性。尽管来自多种鸭跖草属物种的标准化提取物和植物化学物质被认为可以为治疗各种人类疾病提供更安全的替代品,但该属植物的植物化学和药理学尚未得到彻底研究,无论是在各种动物模型的临床前研究中还是在临床前研究中。大规模临床试验。作者还倡导科学家、制药公司所有者和其他感兴趣的各方未来合作开发新型鸭跖草药物。© 2024 作者。
Natural plant-based medicines have gained in popularity, replacing artificial models and chemicals as a result of new pharmacological discoveries. The increased popularity and acceptability of herbal medications such as Commelina arose from the assumption that all-natural products are safe, readily available, and inexpensive. The genus Commelina (Commelinaceae), which has over 200 species, has long been utilized as a treatment for a variety of ailments and conditions around the world. However, to the authors' knowledge, there are no Comprehensive scientific reports of many medicinally important species of the genus Commelina under one roof. The current narrative review aims to present an updated overview of the various species of Commelina focusing on its morphology; geographical distribution; traditional medicinal use (species type, parts of the plant used, the mode of action, ailments treated, and countries practicing); phytochemical constituents; and pharmacological properties. The data search approach was carried out utilizing English-language electronic databases such as PubMed, Web of Science, Scopus, Science Direct, Research Gates, Ethnobotany Research and Applications, and Google Scholar. Using key terms such as "medicinal plant," "genus Commelina," "traditional medicinal usage of Commelina species," "photochemistry of Commelina species," and "pharmacological (biologic) activities of Commelina species" numerous searches and in-depth discussions are conducted. It was found that many Commelina species contain bioactive-phytochemicals (secondary metabolites) with a variety of structural kinds, including alkaloids, phenolics, flavonoids, glycosides, tannins, saponins, sterols, anthocyanins, and others which are presumed for their pharmacological activities. According to the invitro and preclinical reports, the Commelina species have shown anti-diabetic, antioxidant, anti-microbial, analgesic, anti-inflammatory, anti-cancer, hepato-protective, diuretic, fertility-inducing, anti-diarrheal, and anthelmintic activity, sedative, and anxiolytic activities. Although standardized extracts and phytochemicals derived from numerous Commelina species are presumed to provide safer alternatives for treating a variety of human ailments, the phytochemistry and pharmacology of the genus' plants have yet to be thoroughly investigated, both in preclinical studies with various animal models and in large-scale clinical trials. The authors also advocate for future collaboration among scientists, pharmaceutical firm owners, and other interested parties to develop novel commelina drugs.© 2024 The Authors.