masquelet 技术是骨科医生使用的一种两阶段手术，用于治疗继发于感染、创伤和肿瘤切除的大节段性骨缺损。该技术的特点是需要放置临时骨水泥垫片并随后进行骨移植以实现完全重建。我们描述了一个独特的节段性骨丢失重建病例，其中一名患者在不进行骨移植的情况下，经过第一步 masquelet 技术后成功实现了骨折愈合。该病例为一名 21 岁男性，患有开放性股骨骨折，伴有摩托车碰撞后出现 10 厘米的节段性骨质流失。根据 masquelet 技术的第一阶段插入抗生素水泥垫片。由于间隔器周围形成大量骨痂、排列正常且随访时无痛行走，因此未进行进一步的手术干预，聚甲基丙烯酸甲酯间隔器保留在原位。骨折愈合，没有感染，患者仍能负重，没有疼痛。该病例是一个独特的案例，尽管仅完成了 masquelet 手术的第一步，但 10 厘米节段性骨缺损骨折成功愈合。虽然 masquelet 技术被认为是强制性的两步程序，但这种骨骼快速生长和骨折愈合的独特案例值得进一步研究 masquelet 诱导再生而不需骨移植的可能性。版权所有：© Indian Orthopedic Research Group。

The masquelet technique is a two-stage procedure used by orthopedic surgeons to treat large segmental bone defects secondary to infection, trauma, and tumor resection. This technique characteristically requires the placement of a temporary cement spacer and subsequent bone grafting for complete reconstruction. We describe a unique case of segmental bone loss reconstruction in which a patient successfully achieved fracture union after the first step of the masquelet technique without bone grafting.This is a case of a 21-year-old male who presented with an open femur fracture with 10 cm of segmental bone loss after a motorcycle collision. An antibiotic cement spacer was inserted according to the first stage of the masquelet technique. Due to considerable callus formation around the spacer, normal alignment, and pain-free ambulation at follow-up, further surgical intervention was not pursued, and the poly-methyl-methacrylate spacer was left in place. The fracture healed without infection, and the patient remained weight-bearing without pain.This case identifies a unique instance of successful fracture union of a 10 cm segmental bone defect despite the completion of only the first step in the masquelet procedure. While the masquelet technique is believed to be a mandatory two-step procedure, this unique case of rapid bone growth and fracture union warrants further research on the possibilities of masquelet-induced regeneration without bone grafting.Copyright: © Indian Orthopaedic Research Group.