研究动态
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心理干预对癌症患者自杀的影响:系统评价和网络荟萃分析。

The effects of psychological interventions on suicide for cancer patients: a systematic review and network meta-analysis.

发表日期:2024 May 24
作者: Xinyue Zhang, Dan Zhang, Yuqi Liu, Yinong Tian, Feiping Yu, Yingjuan Cao, Yonggang Su
来源: Best Pract Res Cl Ob

摘要:

许多心理干预措施可用于治疗癌症患者的自杀和死亡意念(SDI)以及自杀行为。确定减少癌症患者 SDI 和自杀行为的最佳心理干预措施。然而,目前尚不清楚哪种心理干预最有效。我们通过搜索自成立之日起至 2022 年 4 月 8 日的七个数据库,进行了成对网络荟萃分析。该网络荟萃分析的一个重要重点是比较各种心理干预措施对减少 SDI 和自杀行为的影响在癌症患者中。为了确定疗效,我们使用标准化平均差 (SMD) 和 95% 置信区间 (CI)。此外,还进行了配对荟萃分析、不一致性检验、网络荟萃分析、累积排名曲线下曲面(SUCRA)、比较调整漏斗图、亚组分析和敏感性分析。本研究共检索了 8 项研究,涉及 1,350 名患者。结果表明,六种干预措施中,共情疗法(SUCRA = 95.3%)效果最好。综合心理干预(SUCRA = 77.6%)位居前两位,其次是意义中心治疗(SUCRA = 40.7%)。比较调整漏斗图显示没有显着的发表偏倚。此外,经过敏感性分析后,我们的结论并没有发生明显变化。在这项网络荟萃分析中,共情疗法被认为是减少癌症患者 SDI 和自杀行为的最佳选择。还需要进一步开展多中心、高质量的RCT研究,使我们的结论更加严谨。
Numerous psychological interventions are available for suicidal and death ideation (SDI) and suicidal behavior among cancer patients. To identify the optimal psychological interventions for reducing SDI and suicidal behavior in cancer patients. However, it remains unclear which psychological intervention is the most effective. We performed a pairwise and network meta-analysis by searching seven databases from the date of inception until 8 April 2022. An important focus of this network meta-analysis was the comparison of the effects of various psychological interventions on the reduction of SDI and suicidal behavior among cancer patients. For determining efficacy, we used standardized mean differences (SMDs) and 95% confidence intervals (CIs). Besides, a pairwise meta-analysis, inconsistency test, network meta-analysis, the surface under the cumulative rankings curve (SUCRA), comparison-adjusted funnel plot, subgroup analysis, and sensitivity analysis were also carried out. A total of 8 studies involving 1,350 patients were searched in this study. It showed that empathy therapy (SUCRA = 95.3%) has the best effect among the six interventions. Comprehensive psychological intervention (SUCRA = 77.6%) was ranked in the top two positions, followed by meaning-centered therapy (SUCRA = 40.7%). Comparison-adjusted funnel plots revealed no significant publication bias. In addition, our conclusions have not changed significantly after the sensitivity analysis. In this network meta-analysis, empathy therapy was identified as the optimal choice for reducing SDI and suicidal behaviors in cancer patients. Further multi-center and high-quality RCT studies should be conducted to make our conclusion more rigorous.