对西番莲果实和花的植物化学研究分离出 14 种化合物，其中 5 种是以前未描述过的脂肪酸内酯。通过光谱和光谱数据分析，鉴定出四种 2-吡喃酮，passifetilactones A-D (1-4) 和一种呋喃酮，passifetilactone E (5)。测试了先前未描述的内酯对癌细胞系 HeLa、A549、PC-3、KKU-055 和 KKU-213A 以及两种正常细胞系 Vero 和 MMNK-1 的细胞毒性活性。 Passifetilactones B (2) 和 C (3) 对 6 种细胞系表现出良好至轻度的细胞毒活性，IC50 分别为 3.7-25.9 μM 和 12.2-19.8 μM，但对 MMNK-1 细胞系的活性较弱。在流式细胞术实验中，Passifetilactones B 和 C（2 和 3）显示出对 KKU-055 细胞系的细胞凋亡诱导作用。 Passifetilactone D (4) 是通过硅胶纯化产生的分离产物，但我们证明它也可以在粗 EtOAc 提取物中缓慢形成。这是对该植物的花和果实的首次调查。

Phytochemical investigation of the fruit and flowers of Passiflora foetida led to the isolation of 14 compounds, of which five are previously undescribed fatty acid lactones. Four 2-pyrones, passifetilactones A-D (1-4), and one furanone, passifetilactone E (5), were identified by analysis of spectroscopic and spectrometric data. The previously undescribed lactones were tested for cytotoxic activities against the cancer cell lines HeLa, A549, PC-3, KKU-055, and KKU-213A and two normal cell lines, Vero and MMNK-1. Passifetilactones B (2) and C (3) displayed good to mild cytotoxic activity, at IC50 3.7-25.9 μM and 12.2-19.8 μM, respectively, against six cell lines, but were weakly active against the MMNK-1 cell line. Passifetilactones B and C (2 and 3) showed cell apoptosis induction on the KKU-055 cell line in a flow cytometry experiment. Passifetilactone D (4) is an isolation artifact produced by purification over silica gel, but we demonstrated that it can also be slowly formed within the crude EtOAc extract. This is the first investigation of the flowers and the fruit of this plant.