膀胱内卡介苗 (BCG) 滴注后深部脑刺激系统的牛分枝杆菌感染。
Mycobacterium bovis Infection of a Deep Brain Stimulation System Following Intravesical Bacillus Calmette-Guérin (BCG) Instillation.
发表日期：2024 May 18
作者：
Linda E Spruijt, Arne Mosch, Carel F E Hoffmann, Cees van Nieuwkoop, Jasper D Tijsterman, Rodi Zutt, Niels A van der Gaag, M Fiorella Contarino
来源：
Brain Structure & Function
摘要：
深部脑刺激（DBS）是帕金森病的先进治疗方法。我们描述了一位 71 岁的患者，在膀胱内注射卡介苗作为膀胱癌的辅助治疗后不久，DBS 就感染了牛分枝杆菌。必须更换 DBS 内部脉冲发生器和延长线，并在三个月内使用利福平、异烟肼和乙胺丁醇成功治疗患者。此病例表明医生需要意识到此类感染的风险，并在常规培养中添加特定的分枝杆菌检测。
Deep brain stimulation (DBS) is an advanced treatment in Parkinson's disease. We describe a 71-year-old patient in whom the DBS got infected with Mycobacterium bovis shortly after intravesical BCG instillations as an adjuvant treatment of bladder cancer. The DBS internal pulse generator and extension wires had to be replaced, and the patient was treated successfully with rifampicin, isoniazid, and ethambutol during three months. This case suggests that physicians need to be aware of the risk of this kind of infection and add a specific Mycobacterial test to the regular cultures.