本文报告了 2016-2020 年美国各州癌症发病率生态研究的结果。本研究的目的是确定与 2006 年报告的 1950-1969 年和 1970-1794 年癌症死亡率以及 1998-2002 年癌症发病率的研究结果相比，太阳 UVB 剂量在多大程度上降低了癌症风险并确定哪些因素最近与癌症风险相关。非西班牙裔白人（欧洲裔美国人）男性和女性的癌症数据来自疾病控制和预防中心。获得了 1992 年 7 月地表太阳 UVB 指数，以及 2016 年至 2020 年期间的饮酒、糖尿病和肥胖流行率指数。分析中还使用肺癌发病率作为吸烟、饮食和空气污染的替代指标。太阳 UVB 与降低发病率显着相关的癌症包括膀胱癌、脑癌（男性）、乳腺癌、子宫体癌、食道癌、胃癌、非霍奇金淋巴瘤、胰腺癌和肾癌。肺癌与结直肠癌、喉癌和肾癌显着相关。糖尿病还与乳腺癌、肝癌和肺癌显着相关。肥胖患病率与乳腺癌、结直肠癌和肾癌显着相关。饮酒与膀胱癌和食道癌有关。因此，饮食已成为癌症发病率的一个非常重要的驱动因素。太阳 UVB 在降低癌症风险方面的作用已经减弱，原因是人们在户外的时间减少，使用了可阻挡 UVB 但不能阻挡 UVA 辐射的防晒霜，以及超重和肥胖人群的增加（与较低的 25-25 相关）。羟基维生素 D 浓度和全身炎症的产生，这是癌症的危险因素。一种能够降低糖尿病、肥胖症、肺癌以及癌症风险的饮食方法将主要基于全植物并限制红肉、加工肉类和超加工食品。在涂抹防晒霜之前先接触太阳 UVB 几分钟并服用维生素 D 补充剂也有助于降低患癌症的风险。

This article reports the results of an ecological study of cancer incidence rates by state in the US for the period 2016-2020. The goals of this study were to determine the extent to which solar UVB doses reduced cancer risk compared to findings reported in 2006 for cancer mortality rates for the periods 1950-1969 and 1970-1794 as well as cancer incidence rates for the period 1998-2002 and to determine which factors were recently associated with cancer risk. The cancer data for non-Hispanic white (European American) men and women were obtained from the Centers for Disease Control and Prevention. Indices were obtained for solar UVB at the surface for July 1992, and alcohol consumption, diabetes, and obesity prevalence near the 2016-2020 period. Lung cancer incidence rates were also used in the analyses as a surrogate for smoking, diet, and air pollution. The cancers for which solar UVB is significantly associated with reduced incidence are bladder, brain (males), breast, corpus uteri, esophageal, gastric, non-Hodgkin's lymphoma, pancreatic, and renal cancer. Lung cancer was significantly associated with colorectal, laryngeal, and renal cancer. Diabetes was also significantly associated with breast, liver, and lung cancer. Obesity prevalence was significantly associated with breast, colorectal, and renal cancer. Alcohol consumption was associated with bladder and esophageal cancer. Thus, diet has become a very important driver of cancer incidence rates. The role of solar UVB in reducing the risk of cancer has been reduced due to people spending less time outdoors, wearing sunscreen that blocks UVB but not UVA radiation, and population increases in terms of overweight and obese individuals, which are associated with lower 25-hydroxyvitamin D concentrations and the generation of systemic inflammation, which is a risk factor for cancer. A dietary approach that would reduce the risk of diabetes, obesity, lung cancer, and, therefore, cancer, would be one based mostly on whole plants and restrictions on red and processed meats and ultraprocessed foods. Solar UVB exposure for a few minutes before applying sunscreen and taking vitamin D supplements would also help reduce the risk of cancer.