目的：本研究旨在调查葡萄牙姑息镇静的实践，该国缺乏这方面的数据。方法：这是一项前瞻性多中心研究，包括同意参加的每个团队收治的所有患者。对患者进行随访直至死亡、出院或随访 3 个月后。结果：该研究包括 8 个团队：4 个作为姑息治疗单位 (PCU)，1 个作为医院姑息治疗团队 (HPCT)，2 个作为家庭护理 (HC)，1 个作为 HPCT 和 HC。在入组的 361 名患者中，52% 为男性，中位年龄为 76 岁，其中 285 名患者（79%）患有癌症。 49 名 (14%) 患者接受了持续镇静：其中 26 名 (53%) 为男性，中位年龄为 76 岁。大多数患者 (46 名 (94%)) 患有肿瘤学诊断。仅在少数情况下，家人（16 名）（33%）或患者（5 名）（10%）参与了镇静决定。谵妄是导致镇静的最常见症状。最常用的药物是咪达唑仑（65%）。在多变量分析中，只有年龄和综合评分与镇静独立相关。年龄<76岁的患者和那些痛苦程度较高的患者接受镇静剂的可能性较高。结论：葡萄牙持续姑息镇静的实践在其他研究报告的范围内。一个特别相关的一点是患者及其家属在决策过程中的参与程度较低。每个团队都必须在这方面进行深入的讨论。

Objective: This study aimed to survey the practice of palliative sedation in Portugal, where data on this subject were lacking. Methods: This was a prospective multicentric study that included all patients admitted to each team that agreed to participate. Patients were followed until death, discharge, or after 3 months of follow-up. Results: The study included 8 teams: 4 as palliative care units (PCU), 1 as a hospital palliative care team (HPCT), 2 as home care (HC), and 1 as HPCT and HC. Of the 361 patients enrolled, 52% were male, the median age was 76 years, and 285 (79%) had cancer. Continuous sedation was undergone by 49 (14%) patients: 26 (53%) were male, and the median age was 76. Most patients, 46 (94%), had an oncological diagnosis. Only in a minority of cases, the family, 16 (33%), or the patient, 5 (10%), participated in the decision to sedate. Delirium was the most frequent symptom leading to sedation. The medication most used was midazolam (65%). In the multivariable analysis, only age and the combined score were independently associated with sedation; patients <76 years and those with higher levels of suffering had a higher probability of being sedated. Conclusions: The practice of continuous palliative sedation in Portugal is within the range reported in other studies. One particularly relevant point was the low participation of patients and their families in the decision-making process. Each team must have a deep discussion on this aspect.