本研究调查鼻咽癌（NPC）患者放疗后颈动脉狭窄（CAS）及相关危险因素。观察组由86例复查鼻咽癌患者组成，根据放疗后持续时间分为第1组和第2组， 34名新诊断鼻咽癌患者（0组）。进行颈动脉超声检查和卡方分析。中重度血管异常仅出现在第2组。以轻度血管异常为标准，第2组和第0组总体血管异常率分别为65.9%和41.2%，分别。第2组和第0组中，单侧颈动脉（UCA）、颈总动脉（CCA）、颈内动脉（ICA）和颈外动脉（ECA）的异常率分别为47.4%和30.9%、44.3%和22.1分别为 44.3% 和 16.2%、39.8% 和 5.9%。比较第 1 组和第 0 组，只有 UCA 异常具有统计学意义（45.4% vs. 30.9%）。以中重度血管异常为标准，与第0组相比，第2组的总体血管、UCA、CCA、ICA和ECA异常率较高。复诊年龄超过45岁、T分期和N分期可能会影响CAS。辐射 3 年后 CAS 发病率增加。因此，建议在放射治疗 3 年后定期检查以动态监测 CAS。© 2024。作者。

This study investigated carotid artery stenosis (CAS) and associated risk factors in patients with nasopharyngeal carcinoma (NPC) post-radiotherapy.The observation group comprised 86 reexamined patients with NPC, divided into Group 1 and Group 2 based on post-radiotherapy duration, alongside 34 newly diagnosed patients with NPC (Group 0). Carotid artery ultrasonography and chi-square analysis were performed.Moderate-to-severe vascular abnormalities were exclusively in Group 2. Considering mild vascular abnormalities as the standard, the overall vascular abnormality rates in Group 2 and Group 0 were 65.9% and 41.2%, respectively. In Group 2 and Group 0, the abnormality rates for unilateral carotid artery (UCA), common carotid artery (CCA), internal carotid artery (ICA), and external carotid artery (ECA) were 47.4% and 30.9%, 44.3% and 22.1%, 44.3% and 16.2%, and 39.8% and 5.9%, respectively. Comparing group 1 to group 0, only UCA abnormalities were statistically significant (45.4% vs. 30.9%). Considering moderate-to-severe vascular abnormalities as the standard, Group 2 had higher overall vascular, UCA, CCA, ICA, and ECA abnormality rates compared to Group 0. The age at revisit over 45 years, T stage, and N stage may influence CAS.Radiation increasing CAS incidence after 3 years. So, regular examinations are recommended to dynamically monitor CAS after 3 years of radiotherapy.© 2024. The Author(s).