我们介绍了一位患有癌症的女性的案例，这种癌症削弱了免疫系统并增加了感染风险。因此，感染是癌症的常见并发症。社区获得性肺炎是一种因病原微生物侵入而损害肺实质的急性呼吸道传染病，可因呼吸道败血症而导致呼吸衰竭、多器官功能衰竭。病例报告：38岁混合型- 患有糖尿病且治疗不规范的种族女性，因社区获得性肺炎并发 I 型呼吸衰竭需要机械通气入院。住院期间，尽管经过多次干预，她还是出现了呼吸机相关性肺炎、反复脓胸、支气管胸膜瘘、难治性感染性休克和多器官功能障碍。患者需要长期机械通气、升压药支持和抗生素治疗。 62 天后，诊断出转移性甲状腺乳头状癌。她患有甲状旁腺功能减退症和永久性低钙血症。她因多种并发症和难治性危重症死亡。该病例说明了患有糖尿病和免疫抑制等危险因素的患者患社区获得性肺炎的潜在严重性。它强调了治疗多种合并症的复杂性以及多学科管理和密切监测以及时干预并发症的重要性。© 2024。作者。

We present the case of a woman with cancer, which weakened the immune system and increased the risk of infection. Thus, infections are a frequent complication of cancer. The development of community-acquired pneumonia, an acute respiratory infectious disease that damages the lung parenchyma, caused by the invasion of pathogenic microorganisms, can lead to respiratory failure with multiorgan failure due to respiratory sepsis.Case report of a 38-year-old mixed-race woman with diabetes mellitus and irregular treatment, who was admitted with community-acquired pneumonia complicated by type I respiratory failure requiring mechanical ventilation. During her hospital stay, she developed ventilator-associated pneumonia, recurrent empyema, bronchopleural fistula, refractory septic shock and multiorgan dysfunction despite multiple interventions. The patient required prolonged mechanical ventilation, vasopressor support and antibiotic therapy. After 62 days, metastatic papillary thyroid carcinoma was diagnosed. She presented with hypoparathyroidism and permanent hypocalcemia. She died after multiple complications and a refractory critical condition.The case exemplifies the potential severity of community-acquired pneumonia in a patient with risk factors such as diabetes and immunosuppression. It highlights the complexity of treating multiple comorbidities and the importance of multidisciplinary management with close surveillance for timely interventions for complications.© 2024. The Author(s).