炎症性肠病特异性加速康复外科方案的实施:一项观察性队列研究。
The implementation of an inflammatory bowel disease-specific enhanced recovery after surgery protocol: an observational cohort study.
发表日期:2024 May 25
作者:
V Lin, J K Poulsen, A F Juvik, O Roikjær, I Gögenur, T Fransgaard
来源:
Techniques in Coloproctology
摘要:
加速康复外科 (ERAS) 方案的实施改善了结直肠癌手术的术后结果。关于炎症性肠病 (IBD) 手术的可行性及其对结果影响的证据有限。我们进行了一项回顾性观察队列研究,比较了新西兰大学医院实施 IBD 特异性 ERAS 方案前后的患者轨迹。我们使用 χ2、Mann-Whitney 检验和根据性别调整的优势比,评估了 Clavien-Dindo 3 级或以上严重术后并发症的发生率作为主要结局,术后住院天数和再入院率作为次要结局从 2017 年到 2023 年,394 名患者因 IBD 接受手术并纳入我们的研究。在 ERAS 队列中,39/250 名患者经历了 Clavien-Dindo 3 级或更高级别的术后并发症,而非 ERAS 队列中有 27/144 名患者(15.6% vs. 18.8%,p = 0.420),调整后的比值比0.73(95% CI 0.42-1.28)。与非 ERAS 队列相比,ERAS 队列的术后住院时间显着缩短(中位 4 天与 6 天,p<0.001)。再入院率保持相似(22.4% vs. 16.0%,p = 0.125)。IBD 手术中的 ERAS 与患者更快康复相关,但对严重术后并发症的发生和再入院率没有影响。© 2024。作者( s)。
The implementation of Enhanced Recovery After Surgery (ERAS) protocols has resulted in improved postoperative outcomes in colorectal cancer surgery. The evidence regarding feasibility and impact on outcomes in surgery for inflammatory bowel disease (IBD) is limited.We performed a retrospective observational cohort study, comparing patient trajectories before and after implementing an IBD-specific ERAS protocol at Zealand University Hospital. We assessed the occurrence of serious postoperative complications of Clavien-Dindo grade 3 or higher as our primary outcome, with postoperative length of stay in days and rate of readmissions as secondary outcomes, using χ2, Mann-Whitney test, and odds ratios adjusted for sex and age.From 2017 to 2023, 394 patients were operated on for IBD and included in our study. In the ERAS cohort, 39/250 patients experienced a postoperative complication of Clavien-Dindo grade 3 or higher compared to 27/144 patients in the non-ERAS cohort (15.6% vs. 18.8%, p = 0.420) with an adjusted odds ratio of 0.73 (95% CI 0.42-1.28). There was a significantly shorter postoperative length of stay (median 4 vs. 6 days, p < 0.001) in the ERAS cohort compared to the non-ERAS cohort. Readmission rates remained similar (22.4% vs. 16.0%, p = 0.125).ERAS in IBD surgery was associated with faster patient recovery, but without an impact on the occurrence of serious postoperative complications and rate of readmissions.© 2024. The Author(s).