研究动态
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乳腺癌幸存者慢性疼痛的表型:一项使用癌症疼痛表型 (CANPPHE) 网络多学科国际指南的原始研究。

Phenotyping of chronic pain in breast cancer survivors: an original study using the cancer pain phenotyping (CANPPHE) Network multidisciplinary international guidelines.

发表日期:2024 May 27
作者: Ismail Saracoglu, Meltem Isintas, Ali Turk, Laurence Leysen, Jo Nijs
来源: Best Pract Res Cl Ob

摘要:

这项横断面研究的主要目的是检查乳腺癌幸存者 (BCS) 中疼痛表型的患病率。第二个目标是检查 BCS 中主要疼痛表型与健康相关的生活质量是否存在差异。经历过慢性疼痛的 BCS 被要求填写疼痛数字疼痛评级量表、Margolis 疼痛图和简表 36 (SF-36) 。随后进行问卷调查和定量感官检查。为了确定主要疼痛类型的患病率,使用了癌症疼痛表型 (CANPPHE) 网络最近提出的分类系统。 在 86 名女性参与者中,19 名 (22.09%) 患有主要神经性疼痛,18 名 (20.93%) 患有主要神经性疼痛。显性伤害性疼痛,14 名(16.28%)显性伤害性疼痛。 35 名参与者 (40.70%) 被归类为混合性疼痛。单向方差分析显示,SF-36 的四个疼痛组之间的总体健康状况 (F = 3.205,p = 0.027)、社会功能 (F = 4.093,p = 0.009) 和疼痛 (F = 3.603,p = 3.603,p) 之间存在显着差异。 = 0.017)子量表评分。本研究发现BCS中的疼痛大多是混合表型,其次是神经性疼痛和伤害性疼痛。此外,研究发现,与以神经性疼痛和伤害性疼痛为主的 BCS 相比,以伤害性疼痛为主的 BCS 在身体疼痛和社会功能方面的健康相关生活质量较低。© 2024。作者。
The primary aim of this cross-sectional study is to examine the prevalence of pain phenotypes in breast cancer survivors (BCS). A secondary aim entails examining whether health related quality of life differs between the main pain phenotypes in BCS.BCS who experienced chronic pain were asked to complete the numeric pain rating scale for pain, Margolis pain diagram, and short form 36 (SF-36). Following administration of questionnaires and quantitative sensory examinations were applied. To determine the prevalence of the predominant type of pain, a recently proposed classification system by the Cancer Pain Phenotyping (CANPPHE) Network was used.Of the 86 female participants, 19 (22.09%) had dominant neuropathic pain, 18 (20.93%) had dominant nociceptive pain and 14 (16.28%) had dominant nociplastic pain. 35 participants (40.70%) were classified as having mixed pain. One-way ANOVA revealed a significant difference between the four pain groups for the SF-36 general health (F = 3.205, p = 0.027), social functioning (F = 4.093, p = 0.009), and pain (F = 3.603, p = 0.017) subscale scores.This study found that pain in BCS was mostly of mixed phenotype, followed by predominantly neuropathic and nociplastic pain. Furthermore, it was found that, compared to BCS with predominant neuropathic and nociceptive pain, BCS with predominant nociplastic pain have lower health related quality of life in the areas of bodily pain and social functioning.© 2024. The Author(s).