本研究检验了针对转移性乳腺癌 (MBC) 幸存者的癌症后积极生活 (ALAC) 计划的有效性和可行性。ALAC 是一项为期 12 期的社区计划，旨在通过提高癌症幸存者的身体机能和生活质量来帮助癌症幸存者改善身体机能和生活质量。体力活动。将患有 MBC（IV 期）的 ALAC 参与者与患有早期乳腺癌（I 期和 II 期）的幸存者进行比较。在基线和随访时进行了国际身体活动问卷、戈丁休闲时间身体活动、30 秒坐站测试和 PROMIS 全球健康。在第 12 周评估计划满意度和保留率。使用重复测量混合模型来比较早期乳腺癌幸存者和 MBC 之间的结局变化。总共 585 名女性（59.3 岁 ± 10.6），其中大多数是西班牙裔(54%) 或非西班牙裔黑人 (22%) 被纳入其中（早期，n = 538；MBC，n = 47）。 ALAC 计划后，观察到两名幸存者的体力活动显着增加 (P < 0.001)、身心健康 T 分数改善 (P < 0.001) 以及更多的坐站重复次数 (P < 0.001)早期乳腺癌和 MBC。与早期基线相比，患有 MBC 的女性的身体健康状况 (P = 0.037) 和身体机能 (P = 0.010) 显着较低。ALAC 计划增加了乳腺癌幸存者的体力活动，改善了与健康相关的生活质量和身体机能这项研究强调了将 ALAC 计划等身体活动干预措施纳入癌症幸存者（包括患有转移性疾病的癌症幸存者）综合护理的重要性。© 2024。作者获得独家许可Springer Science Business Media, LLC，隶属于 Springer Nature。

This study examined the effectiveness and feasibility of the Active Living After Cancer (ALAC) program for metastatic breast cancer (MBC) survivors.ALAC is a 12-session community-based program to help cancer survivors improve their physical functioning and quality of life through increased physical activity. ALAC participants with MBC (stage IV) were compared to survivors with early-stage breast cancer (stages I and II). The International Physical Activity Questionnaire, Godin Leisure-Time Physical Activity, 30-second sit-to-stand test, and PROMIS Global Health were administered at baseline and follow-up. Program satisfaction and retention were assessed at week 12. Repeated-measures mixed models were used to compare changes in outcomes between survivors with early-stage breast cancer and MBC.A total of 585 women (59.3 y ± 10.6), most of whom were Hispanic (54%) or non-Hispanic Black (22%), were included (early stage, n = 538; MBC, n = 47). After the ALAC program, a significant increase in physical activity (P < 0.001), improved physical and mental health T-scores (P < 0.001), and more sit-to-stand repetitions (P < 0.001) were observed for both survivors with early-stage breast cancer and MBC. Women with MBC showed significantly lower physical health (P = 0.037) and physical function (P = 0.010) compared to early-stage at baseline.The ALAC program increased physical activity and improved health-related quality of life and physical function among breast cancer survivors with both early-stage and metastatic disease.This study emphasizes the importance of incorporating physical activity interventions like the ALAC program into the comprehensive care of cancer survivors, including those with metastatic disease.© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.