药用植物对于药物的发现至关重要。它们是天然植物化学物质的固有来源，有助于预防和治疗包括癌症在内的多种疾病。本文回顾了南亚和东南亚日常生活中使用的天然膳食产品中植物化学物质在治疗潜在恶性疾病和预防口腔癌方面的有效性的实验和临床证据。该评论还强调了活性植物代谢物、其体外抗增殖特性和靶向信号通路、体内模型中的生物活性以及人类临床试验的转化潜力。© 2024 Wiley periodicals LLC。

Medicinal plants are of prime importance in the discovery of drugs. They are an inherent source of naturally available phytochemicals that can help in the prevention and treatment of several diseases including cancer. This article reviews the experimental and clinical evidence of phytochemicals available in natural dietary products that are used in everyday life across South Asia and South-East Asia for their perceived effectiveness in the management of Potentially Malignant Disorders and prevention of Oral Cancer. The review also highlights the active phytometabolites, their in vitro anti-proliferative properties and targeted signalling pathways, biological activities in in vivo models and translative potential for clinical trials in humans.© 2024 Wiley Periodicals LLC.