其他原因死亡率（OCM）可以作为获得护理的替代指标。作者试图根据计算出的 OCM 风险来比较黑人与白人匹配的前列腺癌特异性死亡率 (PCSM)。对监测、流行病学和最终结果 (SEER) 数据库进行了查询，了解诊断为前列腺癌的黑人和白人之间的情况。 2004年至2009年，收集长期随访资料。 Cox 回归用于使用所有可用协变量计算 OCM 风险。计算出的 OCM 风险用于构建 1:1 倾向评分匹配 (PSM) 队列。然后，竞争风险多变量测试了种族对 PCSM 的影响。总共确定了 94,363 名患者，其中 19,398 名黑人男性和 74,965 名白人男性。中位随访时间 (IQR) 为 11.3 年 (9.8-12.8)。在 10 岁时的非匹配队列中，非西班牙裔黑人 (NHB) 与非西班牙裔白人 (NHW) 患者的 PCSM 和 OCM 分别为 5.5% 和 3.5% 以及 13.8% 和 8.4%（所有 p < .0001）。所有协变量的标准化平均差均<0.15，表明匹配良好。在 10 年匹配队列中，NHB 与 NHW 中的 OCM 分别为 13.6% 和 10.0% (p < .0001)，而 PCSM 分别为 5.3% 与 4.7% (p < .01)。在 PCSM 的竞争风险多变量分析中，黑人男性的风险比为 1.08（95% 置信区间，0.98-1.20），而白人男性的风险比为 p = .13。这项研究的结果显示，黑人和白人患者的 PCSM 相似，与计算出的 OCM 风险相匹配。该报告首次在人口水平上表明种族对 PCSM 没有影响。前列腺癌是男性中一种非常常见的癌症，它与健康差异有关，与白人相比，健康差异对黑人男性的影响更大。关于这两个群体之间的差异是否源于遗传或环境因素的讨论正在进行中。本研究旨在检验基于整体健康状况（健康社会决定因素影响的代理）的匹配是否可以减轻结果的显着差异。当使用前列腺癌以外任何原因的死亡风险进行匹配时，黑人和白人在前列腺癌死亡方面没有显着差异。© 2024 美国癌症协会。

Other-cause mortality (OCM) can serve as a surrogate for access-to-care. The authors sought to compare prostate cancer-specific mortality (PCSM) in Black versus White men matched based on their calculated OCM risk.The Surveillance, Epidemiology, and End Results (SEER) database was queried for Black and White men diagnosed with prostate cancer between 2004 to 2009, to collect long-term follow-up. A Cox regression was used to calculate the OCM risk using all available covariates. This calculated OCM risk was used to construct a 1:1 propensity score matched (PSM) cohort. Then, a competing-risks multivariable tested the impact of race on PCSM.A total of 94,363 patients were identified, with 19,398 Black men and 74,965 White men. The median (IQR) follow-up was 11.3 years (9.8-12.8). In the unmatched-cohort at 10-years, PCSM and OCM were 5.5% versus 3.5% and 13.8% versus 8.4% in non-Hispanic Black (NHB) versus non-Hispanic White (NHW) patients (all p < .0001). The standardized mean difference was <0.15 for all covariates, indicating a good match. In the matched cohort at 10-years, OCM was 13.6% and 10.0% in NHB versus NHW (p < .0001), whereas the PCSM was 5.3% versus 4.7% (p < .01). On competing-risks multivariable analysis on PCSM, Black men had a hazard ratio of 1.08 (95% confidence interval, 0.98-1.20) compared to White men with a p = .13.The results of this study showed similar PCSM in Black and White patients, when matched with their calculated OCM risk. This report is the first to indicate at a population-based level that race has no impact on PCSM.Prostate cancer is a very common cancer among men and it is associated with health disparities that disproportionately impact Black men compared to White men. There is an on-going discussion of whether disparities between these two groups stem from genetic or environmental factors. This study sought to examine if matching based on overall health status, a proxy for the impact of social determinants of health, mitigated significant differences in outcomes. When matched using risk of death from any cause other than prostate cancer, Black and White men had no significant differences in prostate cancer death.© 2024 American Cancer Society.