根据全球最新癌症数据，卵巢癌是所有妇科恶性肿瘤中死亡率最高的，死亡率位居第五位。其病因和发病机制尚不清楚，晚期卵巢癌患者的5年生存率仅为40%（Sung et al. CA Cancer J Clin 71:209-49, 2021）。最近的研究表明，人类微生物群在肿瘤（包括卵巢癌）的发生和进展中发挥着至关重要的作用。大量研究强调了生殖道微生物群、肠道微生物群和卵巢癌之间的复杂联系（Jacobson et al. PeerJ 9:e11574, 2021）。因此，本章将深入探讨卵巢癌微生物群领域中微生物群的组成、功能以及微生物群与免疫之间的相关性，以及细菌在卵巢癌治疗和诊断中的潜力。© 2024。Springer Nature Switzerland AG。

According to the latest global cancer data, ovarian cancer is the deadliest among all gynecological malignant tumors and ranks fifth in terms of mortality. Its etiology and pathogenesis are unknown, and the 5-year survival rate of patients with advanced ovarian cancer is only 40% (Sung et al. CA Cancer J Clin 71:209-49, 2021). Recent research has shown that the human microbiota plays a crucial role in the development and progression of tumors, including ovarian cancer. Numerous studies have highlighted the complex connections between the reproductive tract microbiota, intestinal microbiota, and ovarian cancer (Jacobson et al. PeerJ 9:e11574, 2021). Therefore, this chapter will delve into composition, function, and the correlation between microbiota and immunity in the field of ovarian cancer microbiota, as well as the potential of bacteria in therapeutics and diagnostics of ovarian cancer.© 2024. Springer Nature Switzerland AG.