新颖取代1,3,5-三嗪候选分子的合理设计及其作为高选择性双重IDH1(R132H)/IDH2(R140Q)抑制剂的研宄,针对急性髓系白血病的体内外前临床研究
Rationale design of novel substituted 1,3,5-triazine candidates as dual IDH1(R132H)/ IDH2(R140Q) inhibitors with high selectivity against acute myeloid leukemia: In vitro and in vivo preclinical investigations
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发表日期:2024 Aug
作者:
DOI:10.1016/j.bioorg.2024.107483
摘要
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