研究动态
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皮肤镜结构在预测有色皮肤浅表基底细胞癌中的诊断价值。

Diagnostic Value of Dermoscopic Structures in Predicting Superficial Basal Cell Carcinoma in the Skin of Color.

发表日期:2024
作者: Maryam Khalili, Sare Mirahmadi, Simin Shamsimeymandi, Shahriar Dabiri, Rezvan Amiri, Mohammad Rezaei Zadeh Rukerd, Mahin Aflatoonian
来源: Stem Cell Research & Therapy

摘要:

与白皙皮肤类型的个体相比,深色皮肤个体的基底细胞癌(BCC)表现出不同的皮肤镜模式。本研究旨在探讨皮肤镜检查在区分浅表性 BCC 与其他类型 BCC 方面的诊断效用,特别是对于肤色较深的患者。这项横断面研究重点关注于 2020 年 7 月至 9 月期间被转诊进行皮肤活检的诊断为 BCC 的患者2022年。最初,记录了患者的人口统计学特征、病变的临床特征以及基底细胞癌的病理亚型。随后,采用视频皮肤镜来捕获病变的全面视图和皮肤镜图像。然后利用单变量逻辑回归分析来评估皮肤镜结构在区分浅表性 BCC 与其他 BCC 类型方面的可靠性。最后,该研究评估了皮肤镜检查区分浅表性 BCC 与其他 BCC 亚型的敏感性、特异性、阳性预测值和阴性预测值。该研究纳入了 49 名诊断为 BCC 的患者,平均年龄为 66.22 ± 10.41 岁。年。观察到的最常见的病理亚型是结节性(53.1%)。与肉眼相比,皮肤镜在区分浅表 BCC 与其他类型方面表现出更高的特异性(分别为 55% 和 35%)。单变量分析显示辐条轮结构与浅表性 BCC 之间存在显着相关性(P = 0.02,比值比 = 7.2,95% 置信区间 = 1.35-38.32)。与肉眼相比,皮肤镜检查在区分浅表性 BCC 与其他 BCC 方面表现出优于肉眼的特异性类型。值得注意的是,辐条轮结构表现出与表面 BCC 最强的相关性。版权所有:© 2024 Advanced Biomedical Research。
Basal cell carcinoma (BCC) manifests different dermoscopic patterns in individuals with dark skin complexion compared to those with fair skin types. This study aimed to investigate the diagnostic utility of dermoscopy in discerning superficial BCC from other types of BCC, specifically in patients with dark skin complexion.This cross-sectional study focuses on patients diagnosed with BCC who were referred for skin biopsy between July 2020 and September 2022. Initially, the demographic characteristics of patients, clinical attributes of lesions, and pathological sub-types of BCC were documented. Subsequently, videodermoscopy was employed to capture comprehensive views and dermoscopic images of the lesions. Univariate logistic regression analysis was then utilized to assess the reliability of dermoscopic structures in distinguishing superficial BCC from other BCC types. Last, the study evaluated the sensitivity, specificity, positive predictive value, and negative predictive value of dermoscopy in the differentiation of superficial BCC from other BCC sub-types.The study enrolled 49 patients diagnosed with BCC, with a mean age of 66.22 ± 10.41 years. The most prevalent pathological sub-type observed was nodular (53.1%). Dermoscopy exhibited a higher specificity compared to the naked eye in the differentiation of superficial BCC from other types (55% vs. 35%, respectively). Univariate analysis revealed a significant association between spoke-wheel structures and superficial BCC (P = 0.02, odds ratio = 7.2, 95% confidence interval = 1.35-38.32).Dermoscopy exhibited superior specificity compared to the naked eye in differentiating superficial BCC from other BCC types. Notably, the spoke-wheel structure demonstrated the most robust correlation with superficial BCC.Copyright: © 2024 Advanced Biomedical Research.