调查妇科癌症子宫切除术前后患者盆底疾病 (PFD) 的患病率和严重程度，以及治疗类型和 PFD 以及癌症分期和 PFD 之间的关系；纵向队列研究。妇科肿瘤门诊。因子宫内膜癌、子宫癌、卵巢癌或宫颈癌而接受子宫切除术的患者。参与者在子宫切除术前、子宫切除术后 6 周和 3 个月进行评估。使用广义估计方程或线性混合模型分析随时间的变化。使用逻辑回归模型和方差分析对关联进行分析。失禁严重程度指数、盆底不适量表-简表 (PFDI-20)、女性性功能指数。在 277 名符合条件的患者中，有 126 名参与。子宫切除术之前（尿失禁 [UI] 66%、大便失禁 [FI] 12%、性缺乏活动 73%）和子宫切除术后（UI 59%、FI 14%、性缺乏活动 58%）PFD 患病率较高。与仅接受手术相比，接受辅助治疗导致术后 3 个月出现中度至极重度 UI（比值比 4.98，95% CI 1.63-15.18）。治疗类型与其他 PFD 或癌症分期与任何 PFD 之间均无关联。妇科癌症子宫切除术前后 PFD 的患病率较高。中度至极重度 UI 与辅助治疗相关。© 2024 作者。 BJOG：约翰·威利出版的国际妇产科杂志

To investigate the prevalence and severity of pelvic floor disorders (PFD), and the associations between treatment type and PFD, and cancer stage and PFD in patients before and after hysterectomy for gynaecological cancer; and the changes in outcomes over time.Longitudinal cohort study.Gynaecological oncology outpatient clinics.Patients undergoing hysterectomy for endometrial, uterine, ovarian or cervical cancer.Participants were assessed before, and 6 weeks and 3 months after hysterectomy. Changes over time were analysed using generalised estimating equations or linear mixed models. Associations were analysed using logistic regression models and analyses of variance.Incontinence Severity Index, Pelvic Floor Distress Inventory-short form (PFDI-20), Female Sexual Function Index.Of 277 eligible patients, 126 participated. Prevalence rates of PFD were high before (urinary incontinence [UI] 66%, faecal incontinence [FI] 12%, sexual inactivity 73%) and after (UI 59%, FI 14%, sexual inactivity 58%) hysterectomy. Receiving adjuvant therapy led to moderate-to-very severe UI 3 months after surgery compared with surgery only (odds ratio 4.98, 95% CI 1.63-15.18). There was no association between treatment type and other PFD, or cancer stage and any PFD.Prevalence of PFD was high before and after hysterectomy for gynaecological cancer. Moderate-to-very-severe UI was associated with adjuvant therapy.© 2024 The Author(s). BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd.