研究动态
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患有炎症性肠病和低度肠道 T 细胞淋巴瘤的猫的肠道微生物群。

Gut microbiota in cats with inflammatory bowel disease and low-grade intestinal T-cell lymphoma.

发表日期:2024
作者: Amandine Drut, Héla Mkaouar, Aicha Kriaa, Vincent Mariaule, Nizar Akermi, Tristan Méric, Odile Sénécat, Emmanuelle Maguin, Juan Hernandez, Moez Rhimi
来源: Frontiers in Microbiology

摘要:

在猫和人类中,一些生理和环境因素已被证明可以改变健康个体的肠道微生物群。猫与人类有多种相同的疾病,例如炎症性肠病和低度肠道 T 细胞淋巴瘤。这些慢性肠病的病理生理学知之甚少,但可能涉及肠道微生物群组成的不平衡和正常微生物组活动谱的破坏。由于医疗水平的提高和兽医实践中更容易进行内窥镜检查,这些疾病在猫科动物中被越来越多地诊断出来。这篇综述探讨了健康和慢性肠病猫肠道微生物群的最新数据。此类功能分析将有助于创新诊断工具和针对性治疗策略的进步。版权所有 © 2024 Drut、Mkaouar、Kriaa、Mariaule、Akermi、Méric、Sénécat、Maguin、Hernandez 和 Rhimi。
In cats and humans, several physiological and environmental factors have been shown to alter the gut microbiota of healthy individuals. Cats share several diseases with humans such as inflammatory bowel diseases and low-grade intestinal T-cell lymphoma. The physiopathology of these chronic enteropathies is poorly understood but may involve disequilibrium of the gut microbiota composition and disruption of normal microbiome activity profiles. These disorders are increasingly diagnosed in the feline species due to improved medicalization and easier access to endoscopy in veterinary practice. This review addresses the current data on the gut microbiota of cats in health and in chronic enteropathies. Such functional analysis will help the advancement of innovative diagnostic tools and targeted therapeutic strategies.Copyright © 2024 Drut, Mkaouar, Kriaa, Mariaule, Akermi, Méric, Sénécat, Maguin, Hernandez and Rhimi.