研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

基于金属的方法来对抗宫颈癌。

Metal-based approaches to fight cervical cancer.

发表日期:2024 Jun 27
作者: Diana Pereira, Nuno Alves, Ângela Sousa, Joana F A Valente
来源: DRUG DISCOVERY TODAY

摘要:

宫颈癌(CC)是全球女性死亡的主要原因之一。目前针对这种癌症的治疗方法包括化疗药物、放射治疗、免疫治疗和手术等侵入性方法,这些方法可能会导致严重的副作用并影响患者的生活质量。尽管基于金属的疗法,包括顺铂和钌基化合物,提供了有前途的替代方案,但它们缺乏特异性并损害健康细胞。将金属纳米颗粒与标准方法相结合,在对抗 CC 方面表现出了显着的功效和安全性。总的来说,这篇综述旨在展示基于金属的策略的最新进展和见解,为在对抗 CC 的斗争中更有效、更安全的治疗开辟一条有希望的道路。版权所有 © 2024 作者。由爱思唯尔有限公司出版。保留所有权利。
Cervical cancer (CC) is one of the leading causes of death among women worldwide. The current treatments for this cancer consist of invasive methods such as chemotherapeutic drugs, radiation, immunotherapy and surgery, which could lead to severe side effects and hinder the patient's life quality. Although metal-based therapies, including cisplatin and ruthenium-based compounds, offer promising alternatives, they lack specificity and harm healthy cells. Combining metal nanoparticles with standard approaches has demonstrated remarkable efficacy and safety in the fight against CC. Overall, this review is intended to show the latest advancements and insights into metal-based strategies, creating a promising path for more effective and safer treatments in the battle against CC.Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.