膀胱癌是全球第九大死因，也是巴基斯坦第十四大死因。本研究的目的是确定不同年龄组中尿路上皮癌的发病率、性别分布和分级。该研究纳入了2017年1月至2022年12月期间在白沙瓦白沙瓦医学院病理科收治的131例尿路上皮癌病例；其中男性107人（81.6%），女性24人（18.3%），平均年龄62±13岁。最常见的组织学亚型是乳头状尿路上皮癌，117例（89.3%），其次是鳞状癌和腺癌，5例（3.8%）。大多数高级别尿路上皮癌与肌肉侵犯有统计学意义38(50.66%)。男性患尿路上皮癌的可能性是男性的四倍，而年龄较大的人群患高级别尿路上皮癌的可能性更高。

Bladder cancer is the ninth leading cause of death worldwide and 14th leading cause of death in Pakistan. The objective of this study was to determine the frequency of urothelial carcinoma in various age groups, its gender distribution, and grades. A total of 131 cases of urothelial carcinoma, received at Department of Pathology, Peshawar Medical College, Peshawar, between January 2017 to December 2022, were included in the study; of them 107 (81.6%) were males while 24 (18.3%) were females with a mean age of 62±13 years. The most common histological subtype was papillary urothelial carcinoma in 117(89.3%) cases, followed by Squamous and Glandular in 5(3.8%) cases. Majority of the urothelial carcinoma with high grade showed a statistically significant relation with muscle invasion 38 (50.66%). Males were four times more likely to have urothelial carcinoma while older age groups were more likely to have high grade urothelial carcinoma.