超声造影 (CEUS) 已成为评估微血管形成的诊断工具，对于了解肿瘤发展中的血管生成至关重要。本研究评估了 CEUS 作为 TIRADS 的补充工具在增强基于超声的甲状腺癌诊断方面的有效性。在一年多的时间里，我们使用超声和 CEUS 检查了 133 名患者的 157 个结节（主要是实性甲状腺结节），并接受了甲状腺切除术，以便将超声检查结果与病理报告进行比较。甲状腺癌在 31.21% (49/157) 的患者中被确诊。案例。显着的CEUS高风险特征包括不均匀强化、强化缺陷和完全低强化（AUC分别为0.818、0.767、0.864）。表现出任何这些特征的结节在 CEUS 中被归类为高风险。与CEUS联合使用时，TIRADS的诊断性能得到改善，AUC从0.707增加到0.840，灵敏度也有所提高。CEUS与TIRADS的结合显着提高了甲状腺癌的诊断准确性和特异性。这种组合被证明是一种更有效的风险分层和诊断方法，凸显了 CEUS 作为甲状腺癌评估辅助工具的价值。版权所有 © 2024 Borlea、Moisa-Luca、Popescu、Bende 和 Stoian。

Contrast-enhanced ultrasonography (CEUS) has been established as a diagnostic tool for assessing microvascularization, essential for understanding angiogenesis in neoplastic development.This study assesses the effectiveness of CEUS as a supplementary tool to TIRADS in enhancing the ultrasound-based diagnosis of thyroid cancer.Over one year, 157 nodules in 133 patients, with predominantly solid thyroid nodules, were examined using ultrasound and CEUS and underwent thyroidectomy, allowing for a comparison of ultrasound findings with pathological reports.Thyroid cancer was identified in 31.21% (49/157) of cases. Significant CEUS high-risk features included inhomogeneous enhancement, enhancement defects, and complete hypoenhancement (AUC 0.818, 0.767, 0.864 respectively). Nodules exhibiting any of these features were classified as high-risk in CEUS. The diagnostic performance of TIRADS improved when combined with CEUS, with AUC increasing from 0.707 to 0.840 and improved sensitivity.The integration of CEUS with TIRADS significantly enhances the diagnostic accuracy and specificity in identifying thyroid cancer. This combination proves to be a more effective method for risk stratification and diagnosis, highlighting the value of CEUS as an adjunctive tool in thyroid cancer evaluation.Copyright © 2024 Borlea, Moisa-Luca, Popescu, Bende and Stoian.