全机器人全移植肝移植:迈向未来。
Full Robotic Whole Graft Liver Transplantation: A Step Into The Future.
发表日期:2024 Jul 02
作者:
Hugo Pinto-Marques, Mafalda Sobra, Paolo Magistri, Sílvia Gomes da Silva, Gian Piero Guerrini, Raquel Mega, Cristiano Guidetti, João Santos Coelho, Stefano Di Sandro, Fabrizio Di Benedetto
来源:
ANNALS OF SURGERY
摘要:
报道第一个欧洲系列全机器人全肝移植(RLT)的技术细节和未来展望。迄今为止,采用部分移植物的微创方法进行肝移植的病例报道很少,而且还没有机器人全肝移植的病例。已在科学文献中报道过。所采用的技术是全机器人肝脏切除术,然后通过小中线切口引入移植物后进行机器人植入。肝硬化肝细胞癌(HCC)、尾状叶小、门脉高压程度低、无门肠系膜血栓形成以及 MELD 低的患者被认为是理想的候选者。 2024 年 2 月至 3 月期间,有 6 名患者接受了 RLT在里斯本和摩德纳大学肝移植中心。 RLT期间的热缺血时间为55至90分钟,总手术时间为440至710分钟。中位总手术时间为 595 (±111,3) 分钟。只有一名接受者患有长期高胆红素血症,并得到了安全治疗。中位住院时间为 7.5 天(±4.8 天)。RLT 是一种很有前途的技术,可以进一步减少肝移植的影响,因为它具有较小的切口、温和的组织操作、血管和胆管吻合的高放大倍数和精度,并且减少了肝移植的影响。术后疼痛。这是证明肝移植中微创手术可行性的第一步,尽管还需要进一步的选择和技术改进以提高可重复性。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。
To report the first European series of full robotic whole liver transplantation (RLT) with technical details and future perspectives.Few cases of liver transplantation with a minimally invasive approach using partial grafts have been reported so far, and no cases of robotic whole liver transplantation have been reported in the scientific literature.The adopted technique was full robotic liver hepatectomy, followed by robotic implantation after graft introduction through a small midline incision. Patients presenting with Hepatocellular Carcinoma (HCC) in liver cirrhosis with a small caudate lobe, low degree of portal hypertension, no porto-mesenteric thrombosis, as well as low MELD patients have been considered ideal candidates.Six patients underwent RLT between February and March 2024 at Lisbon and Modena University Liver Transplant Centers. Warm ischemia time during RLT ranged between 55 and 90 min, with a total surgery duration between 440 and 710 min. The median total operative time was 595 (±111,3) minutes. Only one recipient had prolonged hyperbilirubinemia, which was safely treated. The median in-hospital stay was 7.5 days, (±4.8 days).RLT is a promising technique to further reduce the impact of liver transplantation thanks to smaller incision, gentle tissue manipulation, high magnification and precision for vascular and biliary anastomosis, and reduced postoperative pain. This is the first step toward the demonstration of the feasibility of minimally invasive surgery in liver transplantation, although further selection and technical refinements are needed to improve reproducibility.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.