肠内营养是食管癌术后首选的营养方式。然而，肠内营养的首选模式（空肠造口术（FJ）与鼻空肠（NJ）管喂养）仍然存在争议。在这项随机对照试验 (RCT) 中，我们比较了接受食管癌食管裂孔食管切除术 (THE) 的印度患者的 FJ 与 NJ 管饲的安全性、可行性、有效性和生活质量 (QOL) 参数。这项单中心、双臂（FJ 和 NJ 管）、非劣效性随机对照试验于 2020 年 3 月至 2024 年 1 月进行。48 名患者接受了后纵隔胃上拉术，并被随机分配至 NJ 和 FJ臂（每组 24 个）。比较两组术后并发症、导管疗效和生活质量参数，直至随访6周。在本次随机对照试验中，我们发现导管相关并发症的发生率、术后并发症发生率、导管疗效、食管癌 THE 后，NJ 管和 FJ 患者之间的视觉模拟疼痛评分。在出院时（44.7±±6.2 vs 39.8±5.6；p 值，0.005）和 6 周随访时（55.4±±5.2），新泽西组的自我报告身体领域 QOL 评分明显更高vs 48.6 ± 4.5；p 值， < 0.001）。根据我们的 RCT 结果，我们得出结论，两种肠内通路方法（NJ 与 FJ）的导管相关并发症发生率相当。使用 NJ 管是手术 FJ 的可行替代方案，具有早期移除的优点，并避免了与每个腹部插管相关的痛苦。© 2024。作者获得 Springer Science Business Media 的独家许可， LLC，施普林格自然集团的一部分。

Enteral nutrition is the preferred mode of nutrition following esophagectomy. However, the preferred mode of enteral nutrition (feeding jejunostomy (FJ) vs. nasojejunal (NJ) tube) remains contentious. In this randomized controlled trial (RCT), we compared FJ with NJ tube feeding in terms of safety, feasibility, efficacy, and quality-of-life (QOL) parameters in Indian patients undergoing trans-hiatal esophagectomy (THE) for carcinoma esophagus.This single-center, two-armed (FJ and NJ tube), non-inferiority RCT was conducted from March 2020 to January 2024. Forty-eight patients underwent THE with posterior-mediastinal-gastric pull-up and were randomized to NJ and FJ arms (24 in each group). The postoperative complications, catheter efficacy, and QOL parameters were compared between the two groups till the 6-week follow-up.In this RCT, we found no significant difference in the occurrence of catheter-related complications, postoperative complication rate, catheter efficacy, and visual analog pain scores between patients with NJ tube and FJ, following THE for esophageal cancer. There was a significantly better self-reported physical domain QOL score noted in the NJ group, both at the time of discharge (44.7 ± 6.2 vs 39.8 + 5.6; p value, 0.005) and at the 6-week follow-up (55.4 ± 5.2 vs 48.6 ± 4.5; p value, < 0.001).Based on the findings of our RCT, we conclude that both enteral access methods (NJ vs. FJ) exhibit comparable incidences of catheter-related complications. The use of NJ tube is a viable alternative to a surgical FJ, has the benefit of early removal, and saves the distress associated with a tube per abdomen.© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.